Ceftriaxone Sodium Hydrate Injection 2g

Adult administration

For adults and children aged 12 years and older, administer ceftriaxone 1-2g (based on potency) once daily via intravenous or intramuscular injection. In case of severe disease or infections caused by moderately sensitive pathogens, the dose may be increased to 4g (based on potency) once daily. A single 250mg (based on potency) intramuscular injection is recommended for the treatment of gonorrhea. For the prevention of infections before and after surgery, it is recommended to administer 1-2g (based on potency) before surgery, depending on the risk of infection.

Child administration

For newborns (within 14 days old), administer 20-50mg (based on potency) per kg of body weight once daily, not exceeding 50mg (based on potency) per kg. Administer without distinguishing between premature and full-term infants.

This medication should not be mixed with solutions containing calcium or other drugs. Especially in newborns, combining calcium with this medication can lead to precipitate formation and pose risks, so it must not be administered. Patients with a history of allergies to this medication or hypersensitivity to cephalosporins or penicillins should not use it. Additionally, this medication containing lidocaine should not be administered intravenously, nor should it be given to premature infants or newborns with bilirubin binding issues. Patients with a history of drug allergies or allergic dispositions such as bronchial asthma should use this medication cautiously, and patients with severely impaired kidney function may require dose adjustments. Rarely, side effects such as rash, diarrhea, liver function abnormalities, and blood cell count reductions may appear, so any abnormal symptoms should be reported to healthcare professionals immediately. Regular testing such as liver, kidney, and blood tests is needed during treatment, and particular caution is warranted if administering doses over 1g per day due to potential precipitate formation in the gallbladder. There are no specific antidotes for overdose, and treatment should be symptomatic. If dizziness occurs during the use of this medication, driving or operating machinery should be avoided. Pregnant or nursing women should consult with their doctors to make careful decisions regarding the use of this medication. Careful administration is required in children and the elderly, especially in newborns and premature infants, as this medication can elevate bilirubin levels and pose a risk of brain damage. This medication can interact with other drugs, so all concurrent medications should be reported to healthcare professionals. Finally, this medication should be used as soon as possible after preparation, and the recommended storage temperature and duration should be adhered to for safe use.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, peeling skin, pain in oral/ocular mucosa, difficulty or shortness of breath, asthma attacks, respiratory distress with cough and fever, yellowing of skin or eyes (jaundice), extreme fatigue, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urination issues

Mild side effects

• Eosinophilia
• leukopenia
• thrombocytopenia
• diarrhea
• rash
• increased liver enzymes
• headache
• dizziness
• bronchospasm
• loose stools

This medication should be stored in a sealed container to prevent air and moisture entry, and the storage temperature should be maintained between 1 and 30 degrees Celsius. This will help maintain the efficacy of the drug for a longer time.

Appearance

A colorless transparent vial filled with a white to pale yellow crystalline powder.

Package unit

10 vials/box