Celebrex Capsule 200 mg (Celecoxib)

Adult dosage

The minimum recommended dose of this medicine should be adjusted according to the patient, and it may be taken regardless of meals. Osteoarthritis (degenerative arthritis): Take celecoxib 200 mg once daily, or divide the dose into 100 mg twice daily. Rheumatoid arthritis: Take celecoxib 100 mg or 200 mg twice daily. Ankylosing spondylitis (AS): Administer celecoxib 200 mg once daily, or divide the dose into 100 mg twice daily. If no effect is observed after 6 weeks, the dose may be increased to 400 mg daily. If no effect is observed after 6 weeks of treatment with 400 mg daily, another treatment method should be considered. Acute pain and primary dysmenorrhea: The initial recommended dose is celecoxib 400 mg, with an additional 200 mg on the first day of treatment if needed. From the second day of treatment, the recommended dose, if needed, is 200 mg twice daily. Patients with hepatic impairment: For patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This medication should be discussed with a doctor or pharmacist if taken by someone who consumes a lot of alcohol daily, as it may increase the risk of gastrointestinal bleeding. Individuals with heart or vascular issues or risk factors may develop cardiovascular problems such as myocardial infarction or stroke when taking this medication, so it should be used at the lowest effective dose for the shortest duration. Patients with a history of ulcers or gastrointestinal bleeding should exercise caution while taking this medication, as serious issues like gastrointestinal bleeding, ulcers, or perforation may occur. This medication is contraindicated in individuals with certain allergic reactions, severe liver or kidney dysfunction, pregnant or nursing women, or patients with heart disease. Patients with reduced liver or kidney function or existing conditions such as hypertension, heart failure, or asthma should use this medication carefully and frequently monitor their conditions. While taking this medication, various side effects such as dyspepsia, abdominal pain, vomiting, diarrhea, dizziness, headache, skin rash, edema, palpitations, or cough may occur, so any unusual symptoms should be reported to a healthcare professional immediately. As this medication is metabolized in the liver, dosage adjustments or caution is necessary if taken with other medications that affect liver function or liver metabolic enzymes. Pregnant women or women who may become pregnant should not take this medication, and if pregnancy is confirmed during treatment, it should be discontinued immediately. Elderly patients may have reduced kidney, liver, and heart function, requiring closer monitoring when taking this medication. Regular blood tests and liver and kidney function tests are important to check for abnormalities during treatment with this medication. Overdose may result in nausea, vomiting, drowsiness, gastrointestinal bleeding, etc., and in such cases, immediate medical treatment is necessary. This medication is not recommended for children and adolescents as safety and efficacy have not been established for this population. Caution should be exercised with activities requiring concentration, such as driving or operating machinery, while taking this medication.

Gastrointestinal bleeding, cardiovascular thrombotic reaction, myocardial infarction, stroke, upper and lower gastrointestinal perforation, ulcer, bleeding, bronchitis, sinusitis, upper respiratory tract infection, urinary tract infection, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusion, dizziness, muscle tension, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, bloating, gastric ulcer, dental disease, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, elevated liver enzymes, itching, rash, hives, petechiae, angioedema, alopecia, bullous dermatitis, peripheral edema, facial edema, influenza-like illness, injury, taste disturbance, albuminuria, cystitis, hematuria, dysuria, frequent urination, nephrolithiasis, urinary incontinence, urinary tract infection, visual disturbances, cataract, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased serum creatinine, elevated β2-microglobulin, increased NAG, positive urine hematuria, positive urine protein, renal dysfunction, acute renal failure, interstitial nephritis, increased serum sodium, increased serum potassium, elevated BUN, increased CPK, diabetes mellitus, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, increased NPN, increased creatinine, increased alkaline phosphatase, weight gain, anorexia, elevated LDH, hypoglycemia, hyponatremia, bursitis, arthralgia, arthritis, skeletal abnormalities, myalgia, cervical rigidity, synovitis, tendinitis, myositis, leg cramps, fractures, tendon rupture, pain in various areas, muscle stiffness, decreased hematocrit, increased hemoglobin, petechiae, epistaxis, thrombocytopenic purpura, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, granulomatous inflammation, contact dermatitis, injection site reaction, skin nodules, headache, leg cramps, tension headaches, sensory impairment, migraine, neuralgia, neuropathy, sensory abnormalities, cerebral infarction, aseptic meningitis, ataxia, suicide, loss of smell, loss of taste, exacerbation of allergies, allergic reactions, weakness, chest pain, fluid retention, systemic edema, facial edema, fatigue, malaise, fever, facial flushing, influenza-like syndrome, pain, peripheral pain, sepsis, sudden cardiac death, anaphylactic-like reaction, vasculitis, pulmonary embolism, interstitial pneumonia, hepatitis, liver failure, fulminant hepatitis, hepatic necrosis, cholestasis, cholestatic hepatitis, jaundice, photosensitivity reaction, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash with eosinophilia and systemic symptoms, acute generalized pustular exanthema, exfoliative dermatitis, generalized fixed drug eruption, fixed drug eruption, menstrual disorders, female infertility, chest pain, hallucinations, epistaxis, voice disorders, hearing loss, ear abnormalities, otalgia, hearing impairment, cholelithiasis, hepatitis, jaundice, liver failure, fulminant hepatitis, hepatic necrosis, acute renal failure, hyponatremia, tubular interstitial nephritis, nephrotic syndrome, minimal change glomerulonephritis, vasculitis, anaphylactic reaction, pneumonia, herpes zoster, herpes simplex, bacterial infections, fungal infections, soft tissue infections, moniliasis, genital moniliasis, otitis media

This medication should be stored in a tightly sealed container to prevent air or moisture ingress. It is best to maintain a storage temperature between 15 to 30 degrees Celsius.

Appearance

A white capsule filled with a white to off-white powder with a yellow stripe on the top and bottom.

Package unit

30 capsules/bottle, 100 capsules/bottle