Rosugrine 10mg (Rosuvastatin Calcium)

Adult dosage

For the treatment of primary hypercholesterolemia, mixed hyperlipidemia, primary dysbetalipoproteinemia, and homozygous familial hypercholesterolemia, administer once daily at any time of day, irrespective of meals. The initial dosage is 5 milligrams, and the maintenance dosage is 10 milligrams. If necessary, adjust the dosage in increments up to a maximum of 20 milligrams, with an interval of 4 weeks or more.

Children's dosage

For pediatric patients with heterozygous familial hypercholesterolemia (ages 10 to 17), the usual dosing is 5 milligrams to 20 milligrams once daily. The dosage should be adjusted individually based on treatment goals with intervals of 4 weeks or more.

This medication should not be used by individuals who are allergic to specific components. Patients with severe liver dysfunction or unexplained elevated liver enzyme levels should also not take this medication. Individuals with muscle disorders or a history of muscle problems should not use this medication. Particularly in patients taking a medication called cyclosporine, this medication should not be used. Patients with severely impaired kidney function should also avoid this medication. Women who are pregnant or breastfeeding, as well as those who could become pregnant, must consult a physician before using this medication and should use appropriate contraceptive methods. Patients at high risk for muscle-related side effects are prohibited from using high doses of this medication. This medication contains lactose, so individuals with genetic issues like lactose intolerance should not take it. Individuals who consume excessive alcohol or have a history of liver disease should use this medication cautiously and have regular liver function tests. If symptoms such as muscle pain or weakness arise, they should immediately inform their healthcare provider, and this medication may be discontinued if necessary. Caution is required when using this medication in combination with certain drugs, as this may increase blood concentration and the risk of muscle side effects. Since this medication can affect liver and kidney function, regular monitoring is necessary. This medication should not be used during pregnancy or breastfeeding, and women planning to become pregnant should consult their healthcare provider. In the case of overdose, there is no specific antidote, so treatment should be symptomatic while monitoring liver function and muscle enzyme levels. Dizziness may occur when taking this medication, so caution should be exercised while driving or operating machinery. If a rash or severe allergic reaction occurs while taking this medication, it should be stopped immediately and medical assistance sought.

Serious side effects

Hives, hypersensitivity reactions including angioedema, Stevens-Johnson syndrome, drug reaction with eosinophilia and systemic symptoms (DRESS), rhabdomyolysis, severe muscle weakness, myasthenia gravis, jaundice, severe skin reactions, hepatitis, severe edema, acute renal failure, oliguria, severe allergic reactions, severe skin reactions, respiratory distress, liver abnormalities (jaundice), severe neurological symptoms, severe edema or

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• rash
• myalgia
• weakness
• hematuria

This medication should be stored in a tightly closed container to protect it from air and moisture. The recommended storage temperature is room temperature, between 1 and 30 degrees Celsius. This helps maintain the medication's effectiveness and safety for a prolonged period.

Appearance

Pink round film-coated tablets

Package unit

30 tablets (15 tablets/ blister x 2)