Nupito Tablets 20 mg (Atorvastatin Calcium Hydrate)

Adult dosage

The recommended starting dose for the treatment of hyperlipidemia is 10 mg taken once daily. For patients requiring more reduction in LDL cholesterol levels, the dose can be started at 20 mg or 40 mg taken once daily. Dosing should be adjusted within the range of 10-80 mg once daily according to treatment goals and patient response. Lipids should be analyzed within 2-4 weeks after initiation and dose adjustment to determine the necessary changes.

Children's dosage

The recommended starting dose for pediatric patients with heterozygous familial hypercholesterolemia (ages 10-17) is 10 mg once daily, with a maximum dose of 20 mg once daily. Dose adjustments should be made at intervals of 4 weeks or more to meet treatment goals.

This medication may cause adverse muscle symptoms, so if you experience severe muscle pain or weakness or if your creatine kinase levels rise significantly, you should stop taking it immediately and consult your doctor. If you have serious infections, hypotension, major surgery, trauma, metabolic or electrolyte abnormalities, or uncontrolled epilepsy, it may be necessary to temporarily discontinue this medication. This medication should not be used in patients with poor liver function, liver disease, pregnant women or women who might become pregnant, children under 10 years of age, and patients taking certain medications. Patients with a history of alcohol abuse or liver disease, those with reduced kidney function, patients with hypothyroidism, those with a history of muscle disorders, and the elderly should use this medication with caution, and it is important to periodically check muscle and liver function through blood tests before and during treatment. During treatment with this medication, if you experience symptoms such as abnormal liver function, muscle pain, weakness, fever, or fatigue, you must inform your healthcare provider immediately, as discontinuation of the medication may be necessary. Additionally, this medication can interact with various drugs, so if you are taking other medications, be sure to inform your doctor or pharmacist, especially with certain antibiotics, antifungals, antivirals, immunosuppressants, and grapefruit juice. Women of childbearing age must use appropriate contraceptive methods while taking this medication, and if pregnancy is confirmed, they should discontinue use immediately. Nursing mothers should not take this medication, and caution is especially required for children and the elderly when using this medication. In cases of overdose, there is no specific antidote, so you should visit a hospital immediately for symptomatic treatment and blood tests. Finally, this medication should be stored out of reach of children and kept in its original container to prevent misuse or quality degradation.

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweats, pallor, severe rash with high fever, blisters, skin peeling, pain in mucous membranes of the mouth/eyes, shortness of breath or difficulty breathing, asthma attacks, respiratory distress accompanied by cough and fever, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden and severe headache, lightning headache, seizures, altered consciousness, visual disturbances, paralysis, urination problems

Mild side effects

• Fatigue
• malaise
• chest pain
• peripheral edema
• tiredness
• fever
• rhinitis
• hyperglycemia
• hypoglycemia
• weight gain

This medication may be sensitive to air and moisture, so it should be stored in a tightly sealed container. It is best to maintain a storage temperature between 1 and 30 degrees Celsius.

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle