Medication info

Atorvan 40mg (Atorvastatin Calcium Trihydrate)

Prescription medicationTabletExpired
Ingredient · strength
Atorvastatin Calcium Trihydrate›43.38mg / 1 tablet
Manufacturer / importer
동국제약(주)
Appearance
White elliptical film-coated tablet
Packaging
30 tablets/bottle, 100 tablets/bottle
Approval status
Expired

MFDS item code 201901895 · Approved 2019.03.28

This product's status changed to Expired on 2024.03.28. It may no longer be sold, so consult a doctor or pharmacist before taking it.

Summary

Main use
Reduction of risks of myocardial infarction and stroke and improvement of hyperlipidemia
Who uses it
Adults
Adult dosage
The recommended initial dose for the treatment of hyperlipidemia is 10 mg once daily. For patients needing further LDL cholesterol reduction, it may be started at 20 mg or 40 mg once daily. The dosing range should be adjusted within 10–80 mg once daily, personalized according to treatment goals and patient response. For patients with homozygous familial hypercholesterolemia, dosing should be 10–80 mg once daily.

Ingredients

Manufacturer
동국제약(주)

Efficacy & effects

Reduction of risks of myocardial infarction and stroke and improvement of hyperlipidemia

  • Myocardial infarction
  • stroke
  • chronic stable angina
  • retinopathy
  • albuminuria
  • congestive heart failure
  • hypercholesterolemia
  • dyslipidemia
  • abnormal beta-lipoproteinemia
  • elevated serum triglycerides
  • familial hypercholesterolemia
View approved original text

This medication helps reduce the risk of myocardial infarction, stroke, and vascular surgery in adults with multiple risk factors for cardiovascular diseases or patients with type 2 diabetes. It also reduces the incidence of myocardial infarction, stroke, and angina in patients with existing coronary heart disease, while lowering the hospitalization risk due to congestive heart failure. For patients with hyperlipidemia, it improves the blood lipid profile by decreasing total cholesterol, bad LDL cholesterol, apo-B protein, and triglycerides, and increasing good HDL cholesterol. It can enhance therapeutic effects when combined with a diet even in special cases such as familial hypercholesterolemia. This medication is used to promote cardiovascular health and improve dyslipidemia.

Dosage and Administration

Adult dosage

The recommended initial dose for the treatment of hyperlipidemia is 10 mg once daily. For patients needing further LDL cholesterol reduction, it may be started at 20 mg or 40 mg once daily. The dosing range should be adjusted within 10–80 mg once daily, personalized according to treatment goals and patient response. For patients with homozygous familial hypercholesterolemia, dosing should be 10–80 mg once daily.

Precautions

This medication must be discontinued immediately if any abnormal muscle symptoms appear. Particularly, if symptoms like muscle pain, weakness, or cramps are severe or persistent, consult a physician. This medication may affect liver function; therefore, patients with liver disease or elevated liver enzyme levels should not use it. Additionally, if symptoms of liver dysfunction appear, notify healthcare professionals immediately. Women who are pregnant or may become pregnant, as well as those who are breastfeeding, should not take this medication as it may be harmful to fetuses and infants. This medication is not to be used in children under 10 years of age. Additionally, patients with certain genetic metabolic disorders should avoid this medication. Patients with a history of alcoholism or liver disease should use this medication cautiously, and elderly patients should be careful due to the increased risk of muscle-related side effects. This medication may interact with certain drugs. Specifically, when taken with some antibiotics, antifungals, antiviral agents, immunosuppressants, and grapefruit juice, the blood concentration may increase, raising the risk of side effects. Therefore, during treatment, inform the physician or pharmacist of all medications currently being taken and ensure to consult before starting or stopping any new medication. Monitor liver function tests and serum creatine kinase (CK) levels regularly while taking this medication for any signs of abnormalities. This medication should be stored out of reach of children, and it should be kept in its original container to prevent misuse or deterioration of quality. In case of overdose, there is no special antidote, so it is essential to go to the hospital immediately for treatment based on symptoms, and undergo liver function testing and muscle-related tests.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in the mucous membranes of the mouth/eyes, shortness of breath or difficulty breathing, asthma attacks, respiratory distress accompanying cough and fever, jaundice (yellowing of skin or eyes), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, altered consciousness, visual disturbances, paralysis, urination issues

Mild side effects

  • Fatigue
  • lethargy
  • chest pain
  • peripheral edema
  • tiredness
  • fever
  • nasopharyngitis
  • hyperglycemia
  • hypoglycemia
  • weight gain
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  • loss of appetite
  • constipation
  • abdominal bloating
  • dyspepsia
  • nausea
  • diarrhea
  • abdominal pain
  • vomiting
  • belching
  • pancreatitis
  • pharyngeal and laryngeal pain
  • nosebleed
  • insomnia
  • nightmares
  • headache
  • dizziness
  • paresthesia
  • sensory loss
  • taste disturbances
  • amnesia
  • peripheral neuropathy
  • myalgia
  • arthralgia
  • limb pain
  • musculoskeletal pain
  • muscle cramps
  • joint pain

Not everyone experiences these, and they can vary from person to person.

Storage

This medication may be sensitive to air and moisture; therefore, it must be stored in a tightly sealed container. It is recommended to maintain the storage temperature between 1 to 30 degrees Celsius to preserve the medication's effectiveness for a longer duration.

Appearance and packaging

Appearance

White elliptical film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.