Seoul Aspirin Enteric-coated Tablets

Adult dose

Enteric-coated tablets: 1 tablet once daily, taken before meals with sufficient water. Enteric-coated capsules: 1 capsule once daily, taken before meals with sufficient water.

Before taking this medication, those who regularly consume more than three glasses of alcohol daily should consult with a doctor or pharmacist, as there is a risk of gastrointestinal bleeding. This medication should not be used by certain patients, such as those allergic to this drug or other salicylate products, patients with peptic ulcers, aspirin-induced asthma patients, hemophilia patients, those with severe liver or kidney dysfunction, patients with severe heart failure, individuals with a tendency to bleed, those taking high doses of methotrexate, and pregnant women in the third trimester. Care should also be taken when prescribing this medication for patients with a history of renal dysfunction, cardiovascular circulation issues, liver disease, blood disorders, bronchial asthma, pre-operative patients, children under three years of age, those with a history of allergies, elderly patients, those taking anticoagulants, and patients with glucose-6-phosphate dehydrogenase deficiency. During treatment, various side effects may occur, including sudden shock symptoms, anaphylaxis, skin rashes, hives, blood abnormalities, gastrointestinal disturbances, neuropsychiatric symptoms, liver dysfunction, and kidney impairment. If any of these symptoms arise, discontinue use immediately and seek medical attention. This medication carries a significant risk of Reye's syndrome in children under 14 years old with chickenpox or influenza; therefore, it should only be administered cautiously in unavoidable circumstances and the patient's condition should be closely monitored. When taking this medication, chronic or acute health conditions should be considered, and regular clinical examinations should be conducted to monitor for any anomalies during long-term use. Additionally, because this medication exerts antiplatelet aggregation effects, bleeding risks may increase before or after surgical procedures; therefore, consult with a doctor if surgery is planned. Due to numerous interactions with other medications, care should be taken when used with anticoagulants, thrombolytics, diabetes medications, uricosuric agents, methotrexate, lithium preparations, non-steroidal anti-inflammatory drugs, selective serotonin reuptake inhibitors (SSRIs), digoxin, corticosteroids, ACE inhibitors, valproate, alcohol, and others, and consultation with healthcare professionals is essential. During pregnancy, especially in the third trimester, using this medication can result in serious side effects for both the fetus and the mother; thus, it should not be used, and breastfeeding mothers should not take it either. Elderly patients are more susceptible to adverse reactions, so starting with a smaller dose while monitoring their condition is advisable. Finally, as this medication is in an enteric-coated form, care should be taken to avoid damaging the coating, and it is recommended not to take it with other alkalizing agents.

Serious side effects

Hives, severe swelling (edema), difficulty breathing, asthma attacks, shock and anaphylactic symptoms, Stevens-Johnson syndrome, Reye's syndrome, exfoliative dermatitis, severe allergic reactions, liver dysfunction, liver damage due to elevated liver transaminases, acute renal failure, gastrointestinal bleeding, peptic ulcers and perforation, hemolysis and hemolytic anemia, severe edema, bleeding tendency, bleeding risk due to platelet function impairment, intracranial hemorrhage, acute cerebral edema, loss of consciousness

Mild side effects

• Erythema
• itching
• nasal congestion
• rash
• swelling
• rhinitis symptoms
• conjunctivitis
• loss of appetite
• heartburn
• abdominal pain

Drug interactions

This medication may increase the risk of bleeding or decrease renal function when used in combination with other non-steroidal anti-inflammatory drugs and salicylate products. Additionally, using it together with methotrexate doses greater than 15mg can lead to an increased risk of bleeding and impaired renal function. Other interactions also include anticoagulants, ibuprofen, naproxen, and some other non-steroidal anti-inflammatory drugs, thrombolytics, and other antiplatelet agents, and hemostatics.

This medication may be sensitive to air and moisture, so it should be stored in a tightly sealed container. Additionally, it should be kept at room temperature, ideally in a location where the temperature is maintained below 25 degrees Celsius.

Appearance

White, round enteric-coated film-coated tablet

Package unit

30 tablets/bottle, 500 tablets/bottle