Adwin Tablet 20 mg (Atorvastatin Calcium Trihydrate)

Adult dosage

For the treatment of hyperlipidemia, the recommended starting dose of atorvastatin is 10 mg once daily, and for patients requiring greater LDL cholesterol reduction, starting doses of 20 mg or 40 mg once daily may be appropriate. The dosing range is 10 to 80 mg once daily, and it should be individualized based on treatment goals and patient response. Lipid levels should be analyzed 2 to 4 weeks after the start of treatment and/or dose adjustments to inform further dosing.

Children's dosage

For pediatric patients with heterozygous familial hypercholesterolemia (ages 10-17), the recommended starting dose is 10 mg once daily, with a maximum recommended dose of 20 mg per day. Dose adjustments should be based on treatment goals and occur after at least 4 weeks.

This medication may cause muscle-related side effects, so patients should immediately consult a doctor if they experience muscle pain or weakness. Similarly, if there is a significant increase in creatine kinase levels or suspicion of myopathy, the medication should be discontinued. Patients with impaired liver function or liver disease should not be administered this medication or should use it with caution. Women who are pregnant or may become pregnant and nursing mothers should not take this medication. This medication is not to be administered to children, especially those under 10 years old. Patients with a history of alcohol abuse or liver disease, those with decreased kidney function, and elderly patients should exercise more caution when using this medication. This medication may interact with other drugs, so particularly when taken with certain antibiotics, antifungals, protease inhibitors, and some cardiovascular medications, patients should follow their doctor's instructions. If symptoms such as muscle pain, weakness, or fever appear during treatment, patients should immediately notify a hospital for testing. Additionally, if liver function abnormalities occur, the use of this medication should be discontinued and the doctor informed. Regular monitoring of liver function and muscle condition during treatment with this medication is essential. This medication may have increased blood concentration when taken with grapefruit juice, so it is advisable to avoid consuming grapefruit juice. Women requiring contraception should use appropriate contraceptive methods during treatment and should discontinue use immediately upon confirmation of pregnancy. In case of an overdose, as there is no specific antidote, treatment should be based on symptoms, with careful monitoring of liver function and muscle condition.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe rash with fever, blisters, skin peeling, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attacks, cough with fever and abnormal breathing, jaundice (yellowing of skin or eyes), extreme lethargy, sudden severe headache, thunderclap headache, seizures, confusion of consciousness, vision abnormalities, paralysis, coma

Mild side effects

• Weakness
• fatigue
• chest pain
• peripheral edema
• fever
• nasal pharyngitis
• hyperglycemia
• hypoglycemia
• weight gain
• anorexia

This medication should be stored in a tightly sealed container to protect it from air and moisture, and it is best kept at room temperature between 1 and 30 degrees Celsius. Proper storage will maintain the medication's efficacy and allow for safe use.

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle