Previx Duo Capsule

Adult dosage

Administer 1 capsule once daily.

This medication prevents blood from clotting to avoid the formation of clots. However, taking this medication may prolong bleeding times, so if there is severe or persistent bleeding, it is crucial to inform a doctor immediately. Patients must inform healthcare providers about taking this medication before undergoing surgery or starting new medications. Individuals with genetic variants affecting specific enzymes (CYP2C19) may have reduced effectiveness of this medication and may be at increased risk for heart-related problems; caution is advised. Additionally, co-administration of medications that activate CYP2C19 may increase the risk of bleeding, hence such combinations should be avoided. Individuals who consume more than 3 alcoholic beverages daily should consult a doctor or pharmacist before taking this medication, as otherwise, there may be an increased risk of gastrointestinal bleeding. This medication should not be administered to patients with certain conditions. For instance, it should not be used in patients with allergies to this drug or its components, patients allergic to nonsteroidal anti-inflammatory drugs, patients with peptic ulcers or severe bleeding, hemophiliacs, patients with severe liver or kidney dysfunction, pregnant women in the later stages of pregnancy, and nursing mothers. Patients with a history of gastrointestinal bleeding or a tendency to bleed should use this medication cautiously. Particularly, patients scheduled for surgery should discontinue this medication 5-7 days before surgery to reduce bleeding risk before resuming. This medication may increase bleeding risk, and if blood abnormalities or bleeding symptoms are suspected, immediate testing is warranted. Co-administration with anticoagulants like warfarin is not recommended. Rarely, this medication can cause severe blood disorders, such as severe thrombocytopenia or thrombotic thrombocytopenic purpura (TTP); immediate consultation with healthcare providers is necessary if abnormal symptoms occur. During treatment, patients should carefully observe for gastrointestinal symptoms, skin rashes, or respiratory difficulties indicating an allergic reaction. In pregnant women, especially during the third trimester, this medication should not be used; during the first or second trimester, it should only be used cautiously if the benefits outweigh the risks as determined by a physician. Nursing mothers are advised not to take this medication. Safety and efficacy in pediatric and adolescent patients under 18 years have not been established; therefore, it is not recommended. This medication does not affect the ability to drive or operate machinery, but caution is advised due to bleeding risks. Overdosing may significantly increase the risk of bleeding, and as there are no specific antidotes, severe cases may require treatments like platelet transfusions. This medication should be stored at room temperature and kept out of reach of children. While taking this medication, interactions with other drugs may occur, especially with drugs that pose a bleeding risk or affect CYP2C19 enzymes; caution is advised.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweats, pallor, severe rash with high fever, blisters, desquamation, pain in oral/ocular mucous membranes, difficulty or shortness of breath, asthma attacks, respiratory difficulties with cough and fever, jaundice (yellowing of skin or eyes), profound lethargy, sudden and very severe headaches, lightning headaches, seizures, disorientation, visual disturbances, paralysis, urinary changes.

Mild side effects

• Headache
• dizziness
• abdominal pain
• dyspepsia
• diarrhea
• nausea
• rash
• pruritus
• purpura/bruising
• epistaxis

This medication should be stored in a tightly sealed container to prevent exposure to air or light. It is best to maintain a storage temperature between 1 degree and 30 degrees Celsius.

Appearance

An orange hard capsule containing white or pale yellow granules and gastro-resistant coated pellets.

Package unit

30 capsules/bottle, 300 capsules/bottle