Medication info
Cefaclor Capsule 250 mg (Cefaclor Hydrate)

Cefaclor Capsule 250 mg (Cefaclor Hydrate)

Prescription medicationHard capsule경구
Ingredient · strength
Cefaclor Hydrate›250mg / 1 capsule
Manufacturer / importer
(주)시어스제약
Appearance
Hard capsule with upper blue and lower sky blue filled with light yellow powder
Packaging
30 capsules/bottle, 100 capsules/bottle, 300 capsules/bottle,
Approval status
Active

MFDS item code 201800571 · Approved 2018.01.30 · Insurance code 689000280

Summary

Main use
(Respiratory infections) Treatment of pneumonia, pharyngitis, and (urinary infections) pyelonephritis, cystitis
Who takes it
Adults · Children
Adult dose
As cefaclor hydrate, take 250 mg (potency) orally every 8 hours. For severe infections (such as pneumonia) and low sensitivity infections, the dosage can be doubled. In the case of acute gonococcal urethritis, administer this drug 3 g along with probenecid 1 g in a single dose.
Child dose
Administer 20 mg (potency) per kg of body weight divided every 8 hours. For severe infections, otitis media, and infections with low sensitivity, the dosage can be increased to 40 mg (potency) per kg of body weight, with a maximum dose of

Ingredients

Manufacturer
(주)시어스제약

Efficacy & effects

(Respiratory infections) Treatment of pneumonia, pharyngitis, and (urinary infections) pyelonephritis, cystitis

  • Otitis media
  • pneumonia
  • pharyngitis
  • tonsillitis
  • bronchitis
  • pyelonephritis
  • cystitis
  • gonococcal urethritis
  • abscesses
  • furuncles
  • folliculitis
  • cellulitis
View approved original text

This medication is effective against several types of bacteria, including Streptococcus pneumoniae, Haemophilus influenzae, and Staphylococcus aureus. It is used to treat respiratory infections such as otitis media, pneumonia, pharyngitis, tonsillitis, and bronchitis. It is also effective for the treatment of urinary tract infections like pyelonephritis, cystitis, and gonococcal urethritis. Various skin infections such as abscesses, furunculosis, folliculitis, cellulitis, infectious gangrene, subcutaneous abscesses, dermatitis, and wound infections are also treated with this medication. This drug treats various bacterial infections and helps promote quick recovery for patients.

How to take

Adult dose

As cefaclor hydrate, take 250 mg (potency) orally every 8 hours. For severe infections (such as pneumonia) and low sensitivity infections, the dosage can be doubled. In the case of acute gonococcal urethritis, administer this drug 3 g along with probenecid 1 g in a single dose.

Child dose

Administer 20 mg (potency) per kg of body weight divided every 8 hours. For severe infections, otitis media, and infections with low sensitivity, the dosage can be increased to 40 mg (potency) per kg of body weight, with a maximum dose of

Precautions

This drug works by binding to certain proteins and inhibiting the synthesis of bacterial cell walls, leading to bacterial death. Before using this medication, you must inform your doctor if you have experienced severe allergic reactions or shock from it in the past. Additionally, it should not be administered to patients who are allergic to this drug or to cephalosporin antibiotics. Patients allergic to penicillin antibiotics or those with a history of allergies, severely impaired kidney function, those unable to take orally, elderly patients, and patients with a history of gastrointestinal diseases should use this medication cautiously. This medication can rarely cause severe allergic reactions or serious skin reactions, so symptoms should be reported immediately to healthcare personnel. Abnormalities in blood tests, such as leukopenia, anemia, liver dysfunction, and kidney dysfunction, may occur, so regular monitoring is necessary. Gastrointestinal side effects may include diarrhea, abdominal pain, nausea, and vomiting; if severe diarrhea or bloody stools occur, administration should be stopped immediately. Respiratory symptoms or central nervous system abnormalities can also occur, so careful monitoring is required. This drug may cause vitamin K deficiency, so patients prone to bleeding should exercise particular caution. Interactions may occur when used with anticoagulants, diuretics, nephrotoxic antibiotics, etc.; thus, inform healthcare personnel of any currently taken medications. When taken with oral contraceptives, the contraceptive effect may be reduced, so additional contraceptive methods are recommended. Women who are pregnant or breastfeeding should consider the necessity and risks of using this medication, as its safety has not been fully established. It is advisable to avoid the use of this drug in newborns under one month old, as its safety and efficacy have not been confirmed. Elderly patients, whose physical function may be impaired, are at higher risk of side effects and may need dosage adjustments and careful observation. While using this medication, some urine tests may return false positive results, so inform the healthcare personnel about the use of this drug during testing. To prevent the occurrence of resistant bacteria, it is advisable only to use this medication for the minimum duration necessary after susceptibility testing.

Side effects and when to seek care immediately

Serious side effects

  • Urticaria
  • dyspnea
  • Stevens-Johnson syndrome
  • toxic epidermal necrolysis
  • shock
  • anaphylactic symptoms
  • hepatitis
  • jaundice
  • acute renal failure
  • seizures
Show 13 more
  • severe edema
  • hypertension
  • severe colitis
  • asthma
  • interstitial pneumonia
  • eosinophilic pulmonary infiltrates
  • severe allergic reactions
  • severe skin reactions
  • respiratory issues
  • liver abnormalities (jaundice)
  • severe neurological symptoms
  • severe edema
  • or urination issues

Mild side effects

  • Generalized flushing
  • edema
  • angioedema
  • sensory disturbances
  • syncope
  • hypertension
  • vascular dilation
  • rash
  • erythema
  • pruritus
Show 21 more
  • fever
  • lymphadenopathy
  • arthralgia
  • serum sickness-like reactions
  • erythema multiforme
  • arthritis
  • agranulocytosis
  • granulocytopenia
  • pancytopenia
  • anemia
  • thrombocytopenia
  • eosinophilia
  • lymphocytosis
  • leukopenia
  • aplastic anemia
  • hemolytic anemia
  • reversible neutropenia
  • elevations of AST
  • ALT
  • ALP
  • and BUN

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture and should be kept at a temperature between 1°C and 30°C at room temperature. Storing it this way can help maintain the effectiveness of the drug over time.

Appearance and packaging

Appearance

Hard capsule with upper blue and lower sky blue filled with light yellow powder

Package unit

30 capsules/bottle, 100 capsules/bottle, 300 capsules/bottle,

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.