Medication info
Daiyryl Em Tablet

Daiyryl Em Tablet

Prescription medicationTablet경구
Ingredient · strength
Glimepiride›2mg / 1 tabletMetformin Hydrochloride›500mg / 1 tablet
Manufacturer / importer
한국코러스(주)
Appearance
White oval film-coated tablet
Packaging
30 tablets/bottle, 100 tablets/bottle
Approval status
Active

MFDS item code 201800310 · Approved 2018.01.23 · Insurance code 647204930

Summary

Main use
Improvement of blood sugar control in type 2 diabetes
Who takes it
Adults
Adult dose
This medication is administered 1 to 2 times a day just before or with meals. The dosage may be adjusted based on each patient's current therapy, efficacy, and tolerance, requiring adequate blood sugar monitoring. Treatment is generally initiated with a low dose, and adjustments can be made considering the patient's current medications and blood sugar levels. The initial daily dose is Glimepiride/Metformin Hydrochloride 2mg/500mg.

Ingredients

Manufacturer
한국코러스(주)

Efficacy & effects

Improvement of blood sugar control in type 2 diabetes

View approved original text

This medication helps patients with type 2 diabetes better control their blood sugar levels. It is particularly suitable for patients who follow dietary and exercise regimens, as the combined effects of glimepiride and metformin effectively lower blood sugar levels. This supports easy and stable blood sugar management in daily life, significantly aiding in the maintenance of healthy blood sugar levels for patients.

How to take

Adult dose

This medication is administered 1 to 2 times a day just before or with meals. The dosage may be adjusted based on each patient's current therapy, efficacy, and tolerance, requiring adequate blood sugar monitoring. Treatment is generally initiated with a low dose, and adjustments can be made considering the patient's current medications and blood sugar levels. The initial daily dose is Glimepiride/Metformin Hydrochloride 2mg/500mg.

Precautions

This medication can cause severe lactic acidosis or hypoglycemia; therefore, it should be temporarily discontinued and consulted with a doctor if kidney function declines rapidly or if dehydration occurs. It should not be used in patients with impaired kidney function or liver dysfunction, pregnant women, breastfeeding mothers, and patients with certain metabolic acidosis. Elderly patients, those in a state of malnutrition, and patients with irregular meal intake who are at high risk of hypoglycemia should be monitored closely while on this medication. Gastrointestinal disturbances (such as diarrhea, nausea, vomiting, etc.) may commonly occur at the beginning of treatment, but they typically improve over time. This medication can reduce vitamin B12 levels, so regular blood tests to check vitamin B12 status are recommended for long-term use. There are numerous interactions with other medications, so it is essential to inform doctors or pharmacists when starting or stopping new medications, especially those that may affect kidney function. Caution should be exercised while driving or operating machinery, as hypoglycemia may impair concentration. Women who are pregnant or planning to become pregnant should not take this medication and should consider insulin therapy instead. In the event of an overdose, immediate medical attention is required, and if hypoglycemic symptoms occur, sugar intake or emergency care should be sought. This medication's safety and efficacy in children have not been sufficiently established, so special care is needed when used in this population. Regular monitoring of blood sugar levels, kidney function, and blood tests should be conducted to assess therapeutic effects and monitor for side effects. In the event of sudden infections, surgery, dehydration, etc., the administration of this medication should be stopped, and consultation with a doctor is necessary.

Side effects and when to seek care immediately

Serious side effects

  • Urticaria
  • severe swelling (edema)
  • difficulty breathing
  • severe allergic reactions
  • liver damage
  • jaundice
  • cardiac arrest
  • severe lactic acidosis
  • hypoglycemia
  • confusional state
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  • paralysis
  • visual disturbances
  • severe neurological symptoms
  • thrombocytopenic purpura
  • blood abnormalities
  • hemolytic anemia
  • severe edema
  • hypertension
  • severe skin reactions
  • severe rash with fever
  • blisters
  • skin peeling
  • oral/ocular mucosa pain
  • breathing problems
  • heart failure

Mild side effects

  • Diarrhea
  • nausea
  • vomiting
  • abdominal bloating
  • loss of appetite
  • dyspepsia
  • constipation
  • abdominal pain
  • metallic taste
  • visual impairment
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  • taste disturbance
  • erythema
  • itching
  • rash
  • thrombocytopenia
  • leukopenia
  • hemolytic anemia
  • erythrocytopenia
  • agranulocytosis
  • pancytopenia
  • vitamin B12 deficiency
  • increased liver enzymes
  • hepatitis
  • allergic vasculitis
  • photosensitivity
  • decreased serum sodium concentration
  • hypothyroidism
  • diarrhea

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture, ideally at a temperature between 1 and 30 degrees Celsius. Proper storage will help maintain the medication's effectiveness over time.

Appearance and packaging

Appearance

White oval film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.