Medication info
Alphaoin Tablet (R-Tiocitic Acid Trimer Methamine Salt)

Alphaoin Tablet (R-Tiocitic Acid Trimer Methamine Salt)

Prescription medicationTabletOral
Ingredient · strength
R-Thioctic Acid Tromethamine›480mg / 1 tablet
Manufacturer / importer
Daehan New Pharm Co., Ltd.
Appearance
Light green oblong film-coated tablet
Packaging
30 tablets/bottle, 100 tablets/bottle
Approval status
Active

MFDS item code 201708578 · Approved 2017.12.27 · Insurance code 669907200

Summary

Main use
Relief of diabetic polyneuropathy
Who takes it
Adults
Adult dose
Adults: Take 480 milligrams of altioptric acid tromethamine salt once daily with plenty of water, about 30 minutes before breakfast.

Ingredients

Manufacturer
Daehan New Pharm Co., Ltd.

Efficacy & effects

Relief of diabetic polyneuropathy

  • Diabetic polyneuropathy
View approved original text

This medication helps alleviate symptoms caused by diabetic polyneuropathy. It reduces pain and sensory abnormalities due to neuropathy, assisting patients in leading a more comfortable daily life. It effectively improves symptoms and contributes to an improved quality of life.

How to take

Adult dose

Adults: Take 480 milligrams of altioptric acid tromethamine salt once daily with plenty of water, about 30 minutes before breakfast.

Precautions

This medication should not be used in patients with hypersensitivity to R-Tiocitic Acid Trimer Methamine Salt, Thioctic Acid, or its excipients. This medication contains Yellow No. 4 (Tartrazine), and should be used with caution in patients with allergic reactions or hypersensitivity to this ingredient. While taking this medication, various side effects may occur such as sensory abnormalities, pain, headache, constipation, dry mouth, cough, and in some patients, serious adverse reactions like nephrolithiasis may also occur. Particularly, adverse reactions have been reported in patients with diabetic neuropathy, and patients should consult their healthcare provider immediately if symptoms appear. Frequent alcohol consumption may reduce the therapeutic effect of this medication, so it is advisable to avoid alcohol as much as possible. Taking this medication with iron, magnesium preparations, or milk may hinder proper absorption in the body, thus dosing intervals should be observed. Furthermore, when used in conjunction with insulin or other diabetes medications, blood sugar levels may drop too low, so blood sugar levels should be monitored regularly, and medication dosages must be adjusted as necessary. Pregnant or breastfeeding women should use this medication only under a physician’s judgment after considering the benefits and risks. There is no experience using this medication in children under 18 years old, therefore it is safer not to administer it to this age group. In cases of overdose, severe toxic symptoms may present, such as altered consciousness, generalized convulsions, hypoglycemia, and dysfunction of multiple organs, so immediate medical attention should be sought for appropriate treatment. This medication should be stored in a tightly closed container to avoid exposure to air or humidity. It should not be kept at temperatures above 30 degrees Celsius and must be kept out of reach of children, and transferring it to another container should be avoided.

Side effects

  • Paresthesia
  • pain
  • sensory loss
  • headache
  • constipation
  • abdominal discomfort
  • nasopharyngitis
  • dry mouth
  • cough
  • cystitis
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  • diarrhea
  • burning sensation
  • nephrolithiasis
  • mouth dryness
  • myalgia
  • nausea
  • loss of appetite
  • arthralgia
  • palpitations
  • insomnia
  • upper limb fracture
  • hypoglycemia
  • neurogenic bladder
  • diabetic retinopathy
  • colitis
  • benign gastric neoplasm
  • gastrointestinal bleeding
  • disease worsening
  • soft tissue inflammation
  • cold
  • body aches
  • plantar fasciitis
  • disc herniation
  • thyroiditis
  • increased LDH
  • increased triglycerides
  • weight loss
  • abnormal blood sugar
  • dysuria
  • worsening kidney function impairment
  • vaginitis
  • conjunctivitis
  • floaters
  • unspecified retinal vascular disorder
  • heart palpitations
  • acute abdomen
  • colon polyp
  • benign oral neoplasm
  • benign gastrointestinal neoplasm
  • gastroesophageal reflux disease
  • gastritis
  • gastroenteritis
  • dental caries
  • periodontitis
  • anal bleeding
  • chest pain
  • peripheral edema
  • swelling
  • limb pain
  • carpal tunnel syndrome
  • side pain
  • generalized edema
  • generalized weakness
  • low back pain
  • sleep disorder
  • simple partial seizure
  • facial paralysis
  • bitter taste
  • genital pruritus
  • nail changes
  • blisters
  • dermatitis
  • unspecified peripheral vascular disease
  • gum bleeding
  • phlegm disease
  • bronchitis
  • throat infection
  • sinusitis
  • congestion
  • upper respiratory infection
  • allergic atopic rhinitis
  • dyspnea
  • nausea
  • vomiting
  • gastrointestinal pain
  • skin rash
  • hives
  • itching
  • dizziness
  • sweating
  • taste disturbance
  • upper abdominal pain
  • dyspepsia
  • pruritus
  • abdominal pain
  • heartburn
  • restlessness
  • altered consciousness
  • generalized convulsions
  • lactic acidosis
  • shock
  • rhabdomyolysis
  • hemolysis
  • disseminated intravascular coagulation
  • bone marrow suppression
  • multiple organ failure

Not everyone experiences these, and they can vary from person to person.

Storage

This medication must be stored in a sealed container to prevent exposure to air or moisture. It is important to maintain a storage temperature between 1 degree and 30 degrees Celsius. This will help retain the efficacy of the medication for a longer period.

Appearance and packaging

Appearance

Light green oblong film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.