Selenium Plus Injection (Aselenic Acid)

Adult dosage

In adults, during stable metabolism with parenteral nutrition (TPN), inject 20 to 40 μg of selenium per day.

Children's dosage

In children, inject 3 μg per kg of body weight per day.

This medication contains selenium, so it should not be used in patients with selenium toxicity. If overdosed, toxicity may occur, so treatment should be discontinued immediately if unusual symptoms develop. Administration without dilution directly into a peripheral vein may cause phlebitis, so it must be diluted before use. Since this medication is a stable solution, it must be mixed with other solutions before administration. It should be administered carefully in patients with impaired kidney function or in premature infants, and caution is needed due to the risk of aluminum accumulation with long-term parenteral administration. Rarely, pain or allergic reactions may occur during injection; thus, consult a doctor or pharmacist if such symptoms arise. If symptoms such as dermatitis, odor during sweating or breathing, hair loss, anxiety, or vomiting occur, discontinue use and consult a specialist. Before administration, visually inspect for any precipitate or discoloration, and it is important to prepare it in an aseptic environment. In cases of renal or gastrointestinal dysfunction, selenium excretion may be difficult, so dosage adjustment is necessary. In blood transfusion patients, selenium levels should be continuously monitored to consider its quantity in blood. Pregnant women or women of childbearing potential should use this medication only when the therapeutic benefits outweigh the risks to the fetus, as it can affect fetal development. For lactating women, as the safety of this medication is not established, it is advisable to discontinue breastfeeding or to stop the medication use. Overdose may result in chronic symptoms such as dermatitis, vomiting, metallic taste, hair loss, anxiety, and depression, and in severe cases, life-threatening acute reactions may occur, necessitating immediate treatment. In cases of overdose, gastric lavage, inducing diuresis, or administration of high-dose vitamin C may be required, and in very severe cases, dialysis may be needed to remove selenium. Keep this medication out of the reach of children, use it immediately after opening, and transferring to another container may not be good for maintaining quality.

Serious side effects

• Acute peripheral vascular collapse
• internal vascular hyperemia
• pulmonary hemorrhage
• congestion
• edema
• gastric mucosal erythroplasia
• death

Mild side effects

• Pain
• allergic reactions
• dermatitis
• odor during sweating or breathing
• hair loss
• anxiety
• vomiting
• oral disorders
• gastrointestinal disturbances
• tension

Store this medication in a sealed container to prevent air ingress and maintain a storage temperature between 15 to 30 degrees Celsius. This will help preserve the efficacy of the medication and prevent deterioration.

Appearance

A colorless, odorless, transparent liquid contained in a colorless, transparent vial for injection

Package unit

10 milliliters/vial x 10