Medication info
Twintel Tablets 40/5mg

Twintel Tablets 40/5mg

Prescription medicationTablet경구
Ingredient · strength
Telmisartan Powder 23.9%›167.36mg / 1 tabletTelmisartan›40mg / 1 tabletAmlodipine Besylate›6.935mg / 1 tablet
Manufacturer / importer
구주제약(주)
Appearance
<For domestic use> A white and light gray double-faced oval-shaped tablet. <For export> A white or whitening rectangular tablet.
Packaging
30 tablets (10 tablets/PTP*3)
Approval status
Active

MFDS item code 201706196 · Approved 2017.07.26 · Insurance code 669804900

Summary

Main use
Improvement of blood pressure in essential hypertension not controlled by monotherapy with telmisartan or amlodipine.
Who takes it
Adults · Children
Adult dose
The recommended dose is 1 tablet once daily, to be taken with water regardless of meals. It is advisable to take it at the same time each day (e.g., morning). For patients with kidney dysfunction, treatment should start at a low dose in severe cases, and the dose should be gradually increased. For patients with liver dysfunction, the daily dose of telmisartan should not exceed 40 milligrams. In elderly patients (75 years and older), low dosing should be initiated.
Child dose
The safety and efficacy of this medication in pediatric patients under 18 years of age have not been established; therefore, administration is not recommended.

Ingredients

Manufacturer
구주제약(주)

Efficacy & effects

Improvement of blood pressure in essential hypertension not controlled by monotherapy with telmisartan or amlodipine.

  • Essential hypertension
View approved original text

This medication is used for patients with essential hypertension whose blood pressure is not sufficiently controlled by monotherapy with telmisartan or amlodipine. Essential hypertension refers to a condition where blood pressure remains persistently high, and effective management is essential to prevent cardiovascular complications. This medication helps lower blood pressure into the normal range, improves vascular health, and reduces cardiac strain. Thus, it is suitable for patients who have difficulty controlling hypertension and assists in managing blood pressure with regular use.

How to take

Adult dose

The recommended dose is 1 tablet once daily, to be taken with water regardless of meals. It is advisable to take it at the same time each day (e.g., morning). For patients with kidney dysfunction, treatment should start at a low dose in severe cases, and the dose should be gradually increased. For patients with liver dysfunction, the daily dose of telmisartan should not exceed 40 milligrams. In elderly patients (75 years and older), low dosing should be initiated.

Child dose

The safety and efficacy of this medication in pediatric patients under 18 years of age have not been established; therefore, administration is not recommended.

Precautions

This medication can cause serious harm to the fetus if taken during pregnancy, particularly in the second and third trimesters; therefore, women who are pregnant or may become pregnant should not take it. Additionally, patients with hypersensitivity to any ingredient of this medication, biliary obstruction, severe liver disease, serious heart issues, severe hypotension, or those in cardiac shock should not use this medication. Patients with primary aldosteronism, certain heart valve diseases, liver disease, gastrointestinal diseases, renal artery hypertension, dialysis patients, and the elderly require special caution when taking this medication. This medication may cause various side effects such as dizziness, peripheral edema, palpitation, hypotension, dyspepsia, and liver dysfunction; if any abnormal symptoms occur, consultation with medical professionals should be sought immediately. During pregnancy, the use of this medication may lead to fetal kidney dysfunction, oligoamnios, and skull formation abnormalities; if pregnancy is confirmed, it should be stopped immediately. Women who are breastfeeding should also refrain from taking this medication as its ingredients may be transmitted through breast milk. The safety and efficacy of this medication have not been established in pediatric patients under 18 years of age, and it is not recommended for them. In elderly patients, dosage should be adjusted and increased slowly to ensure safety. Overdose may result in severe hypotension, dizziness, and heart rate abnormalities, requiring immediate emergency treatment. This medication may interact with other drugs, so patients, especially those with impaired kidney function or specific heart diseases, must consult a physician or pharmacist before taking it. While taking this medication, drowsiness or dizziness may occur, hence caution is needed while driving or operating machinery. Finally, it is important to keep this medication out of the reach of children, store it in its original packaging, and take it immediately after opening.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in oral/ocular mucosa, difficulty breathing or breathlessness, asthma attacks, respiratory distress accompanied by cough and fever, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden and severe headaches, lightning headaches, seizures, confusion of consciousness, visual disturbances, paralysis, reduced urine output.

Mild side effects

  • Dizziness
  • peripheral edema
  • upper respiratory tract infection
  • urinary tract infection
  • anemia
  • hyperkalemia
  • hypoglycemia
  • hyponatremia
  • hyperglycemia
  • depression
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  • insomnia
  • anxiety
  • confusion
  • drowsiness
  • migraine
  • headache
  • sensory disorders
  • visual impairment
  • vertigo
  • tinnitus
  • palpitations
  • bradycardia
  • tachycardia
  • flushing
  • hypotension
  • orthostatic hypotension
  • cough
  • nausea
  • vomiting
  • dyspepsia
  • abdominal pain
  • diarrhea
  • dry mouth
  • itching
  • rash
  • hair loss
  • vascular edema
  • eczema
  • erythema

Not everyone experiences these, and they can vary from person to person.

Storage

This medication is sensitive to light and should be stored in a container that does not allow light to enter. Additionally, it should be stored at room temperature between 1 to 30 degrees Celsius to maintain its efficacy.

Appearance and packaging

Appearance

<For domestic use> A white and light gray double-faced oval-shaped tablet. <For export> A white or whitening rectangular tablet.

Package unit

30 tablets (10 tablets/PTP*3)

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.