Combiron Tablets 10/8 Milligrams

Adult dose

In adults, Candesartan Cilexetil is to be taken orally once daily at a dosage of 8-16 mg for the treatment of essential hypertension. If blood pressure is not adequately controlled after 4 weeks of treatment, the dosage may be increased to a maximum of 32 mg once daily. For heart failure treatment, the initial dosage is 4 mg once daily, and the dosage may be doubled at intervals of no less than 2 weeks, up to a maximum of 32 mg once daily. Rosuvastatin is used for primary hyperlipidemia

Child dose

The safety and efficacy in adolescents and children under 18 years have not been established, therefore it is not administered.

This medication can cause severe harm to the fetus and newborn if taken during pregnancy, particularly in the second and third trimesters. It must be discontinued immediately if pregnancy is confirmed. It should not be used in patients with hypersensitivity to this medication, severe liver disease, severely impaired kidney function, pregnant or breastfeeding women, or patients with muscle disorders. Elderly patients or those with hyperkalemia, liver disorders, heart disease, or kidney transplant patients should use this medication with caution, and extra caution is necessary if there is a high risk of muscle pain or myopathy. During treatment with this medication, side effects such as headaches, itching, dyspepsia, and muscle pain may occur, so patients should consult with a doctor if symptoms are severe. If any muscle-related adverse symptoms occur, the patient should immediately inform the doctor and confirm muscle damage through blood tests, and may need to stop taking the medication in severe cases. This medication may interact with other antihypertensive agents, diuretics, anticoagulants, etc., so any other medications being taken should be reported. Pregnant or breastfeeding women should not use this medication, and women of childbearing potential should use appropriate contraception. This medication has not been established as safe and effective for children and is not recommended for their use. Elderly patients should take it cautiously while periodically monitoring kidney function and blood pressure. In case of overdose, symptoms such as hypotension and dizziness may occur, and appropriate treatment should be sought immediately at a medical facility. Care should be taken due to the possibility of dizziness caused by hypotension during driving or operating machinery.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in mucous membranes of mouth/eyes, difficulty breathing or shortness of breath, asthma attack, respiratory issues accompanied by cough and fever, yellowing of skin or eyes (jaundice), extreme lassitude, sudden and severe headache, lightning headache, seizures, confusion, visual disturbances, paralysis, urination

Mild side effects

• Headache
• dizziness
• nasopharyngitis
• itching
• generalized itching
• nausea
• fatigue
• dermatitis
• musculoskeletal pain
• throat pain

This medication may be sensitive to air and moisture; therefore, it should be stored in a sealed container. It is recommended to maintain a storage temperature between 1°C and 30°C to safely preserve the medication's efficacy.

Appearance

Pink round film-coated tablets

Package unit

30 tablets (10 tablets/PTP X 3)