Lipikrin Tablet 10mg (Atorvastatin Calcium Trihydrate)

Adult dosage

It can be taken at any time of day, regardless of food. The recommended starting dose for hyperlipidemia is 10 mg once daily, and if a greater reduction in LDL cholesterol is required, it may be started at 20 mg or 40 mg once daily (only if a reduction of 45% or more in LDL cholesterol is needed). The dosing range is 10 to 80 mg once daily. The initial and maintenance doses should be individualized based on treatment goals and responses, and lipid levels should be analyzed within 2 to 4 weeks after treatment initiation and/or dose adjustment, and doses should be adjusted accordingly. The treatment goal is to lower LDL cholesterol levels, so it is recommended to use LDL cholesterol to evaluate treatment initiation and response. However, if LDL cholesterol levels cannot be used, total cholesterol may be used to monitor treatment response. For patients with homozygous familial hypercholesterolemia, the dosing is 10 to 80 mg once daily, given in conjunction with other lipid-lowering therapies (e.g., LDL apheresis) or when such therapies are not available. For pediatric patients with heterozygous familial hypercholesterolemia (ages 10-17), the recommended starting dose is 10 mg once daily, with a maximum recommended dose of 20 mg daily (there is no clinical data in the pediatric population for dosing greater than 20 mg). The dosing may be appropriately increased or decreased based on individual patient treatment goals. Doses should be adjusted at intervals of 4 weeks or more. ○ Renal impairment: Renal disease does not affect the plasma concentration of atorvastatin or its LDL cholesterol-lowering effect, so dose adjustment is not needed. ○ Elderly: The efficacy and safety for patients aged 70 and older are similar to those in the general adult population.

Children's dosage

The recommended starting dose for pediatric patients with homozygous familial hypercholesterolemia (ages 10-17) is 10 mg once daily, and the recommended maximum dose is 20 mg once daily. The dosing may be adjusted at intervals of 4 weeks or more.

This medication may cause muscle-related problems; therefore, if symptoms of muscle pain or weakness arise, treatment should be stopped immediately, and consultation with a physician is required. Patients with impaired liver function or active liver disease should not take this medication. Women who are pregnant or may become pregnant should not take this medication and must use adequate contraceptive methods during treatment. Breastfeeding women should also avoid this medication and discontinue nursing. This medication is not for children under 10 years old. Patients with a history of alcohol abuse or liver disease should use this medication cautiously and undergo regular liver function tests. The risk of side effects may increase when taken with certain medications; hence, it is essential to inform a doctor or pharmacist if taking other medications. Severe muscle diseases such as myopathy or rhabdomyolysis may pose serious risks; therefore, if muscle pain is severe or persistent, inform medical personnel immediately. This medication can cause various side effects such as liver dysfunction, allergic reactions, skin rashes, gastrointestinal symptoms, etc.; if abnormal symptoms arise, consult a physician immediately. Elderly patients or those with poor kidney function are at higher risk of muscle-related side effects when taking this medication; caution is advised. There is no specific antidote for overdose; treatment should be symptomatic, and regular monitoring of liver function and muscle-related parameters should be conducted. This medication should be stored out of the reach of children and kept in its original container to maintain its quality and safety.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe allergic reactions, severe rash with high fever, blisters, mucous membrane pain in the mouth/eyes, severe skin reactions, difficulty breathing or shortness of breath, asthma attacks, respiratory issues associated with cough + fever, respiratory problems, yellowing of the skin or eyes (jaundice), extreme lethargy, liver abnormalities (jaundice), sudden and

Mild side effects

• Weakness
• fatigue
• chest pain
• peripheral edema
• tiredness
• fever
• nasopharyngitis
• hyperglycemia
• hypoglycemia
• weight gain

This medication should be stored in a tightly sealed container to prevent air exposure and kept at room temperature between 1 and 30 degrees Celsius for safety. Storing it this way will maintain the drug's efficacy and prevent degradation.

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle