Nelfra 20 mg (Esomeprazole Magnesium Trihydrate)

Adult dosage

This medication should be swallowed whole with liquid such as water and should not be chewed or crushed. 1. Gastroesophageal reflux disease (GERD) - Treatment of erosive esophagitis: 40 mg once daily for 4 weeks - If treatment fails or symptoms persist, an additional 4 weeks of dosing - Maintenance therapy to prevent recurrence in esophagitis: 20 mg once daily - Treatment for symptoms of gastroesophageal reflux disease without esophagitis:

Children's dosage

Adolescents aged 12 years and older - Gastroesophageal reflux disease (GERD) - Erosive esophagitis treatment: 40 mg once daily for 4 weeks - Additional 4 weeks in case of treatment failure - For gastroesophageal reflux disease without esophagitis:

This medication should not be administered to patients who have allergic reactions or hypersensitivity to specific ingredients. In particular, patients who are allergic to penicillins, macrolide antibiotics, those taking specific heart-related medications, and nursing women should avoid using this medication. This medication contains Yellow No. 5 (Tartrazine), and patients with allergies to this component should be cautious. During use, various side effects such as headache, dizziness, abdominal pain, diarrhea, and skin rash may occur, so if any abnormal symptoms appear, immediate consultation with a doctor is necessary. Especially, if symptoms such as muscle pain, weakness, or arrhythmias occur, stop taking the medication immediately and seek medical evaluation. This medication can lower gastric acidity, increasing the risk of bacterial infections, so if diarrhea persists or worsens, inform healthcare providers. Long-term use may increase the risk of bone fractures, so patients at risk for osteoporosis should undergo regular examinations. Additionally, this medication can lower serum magnesium levels, so patients using it long-term or in combination with certain diuretics should periodically check their magnesium levels. The safety of this medication during pregnancy has not been sufficiently confirmed, so pregnant women should consult a doctor before use. Nursing women are advised not to take this medication. In case of overdose, there is no specific antidote, so appropriate treatment should be provided based on symptoms, and it should be stored out of reach of children. Furthermore, this medication may interact with various drugs, so it is essential to inform medical professionals if other medications are being taken. Regular monitoring of symptoms and test results is important while taking this medication, and immediate consultation with professionals is necessary if any unusual symptoms occur.

Serious side effects

Urticaria, angioedema, anaphylactic reaction/shock, severe rash with high fever, blisters, skin peeling, pain on mucous membranes of mouth/eyes, bronchospasm, difficulty breathing or shortness of breath, jaundice, hepatitis, hepatic failure, encephalopathy, acute generalized exanthematous pustulosis, Stevens-Johnson syndrome, toxic epidermal necrolysis (Lyell's syndrome), drug reaction with eosinophilia and systemic symptoms (DRESS syndrome), severe edema.

Mild side effects

• Leukopenia
• thrombocytopenia
• fever
• angioedema
• peripheral edema
• hyponatremia
• hypomagnesemia
• insomnia
• anxiety
• mental confusion

This medication must be stored in a tightly sealed container to prevent exposure to air or moisture. Additionally, it is important to maintain storage temperature between 1 degree and 30 degrees Celsius to ensure the medication's effectiveness.

Appearance

Pale pink rectangular film-coated tablet

Package unit

28 tablets (14 tablets/Alu-Alux2)