Lisednil Plus Tablet

Adult dose

Take 1 tablet of this medication by mouth once a week. Since food interferes with the absorption of this medication, take it at least 30 minutes before breakfast or at least 2 hours before or after consuming any food or drink during the day. Take it upright with a sufficient amount of pure water (170-230 mL); do not chew or suck on it. Do not lie down for at least 30 minutes after taking it.

This medication can irritate the gastrointestinal mucosa, which may lead to esophageal problems such as esophagitis or esophageal ulcers. If symptoms such as difficulty swallowing, pain behind the sternum, or heartburn occur during use, discontinue use immediately and consult a physician. Take this medication with a sufficient amount of water (170-230 mL), and do not lie down for at least 30 minutes after taking it. Patients with esophageal motility disorders, hypocalcemia, or severe renal impairment should not take this medication. This product contains lactose and should not be used by patients with lactose intolerance. It is advisable not to take this medication with drugs or food containing divalent cations such as calcium or magnesium. This medication may require supplementation if calcium and vitamin D intake is insufficient, particularly in patients receiving long-term steroid therapy. Consult a specialist before dental treatment, as there is a risk of jaw osteonecrosis. Pregnant or nursing women should consult their physician before use, and it is recommended to discontinue use or breastfeeding during treatment. Safety and efficacy in children have not been established; hence, use should be cautious. Elderly patients can use it without special caution, but must be closely monitored for dosing and adverse reactions. In case of overdose, serum calcium and phosphorus levels may decrease; if hypocalcemia symptoms appear, immediate treatment is required.

Serious side effects

• Severe esophagitis
• esophageal ulcers
• esophageal strictures
• perforation
• Stevens-Johnson syndrome
• toxic epidermal necrolysis
• angioedema
• severe rash
• blisters
• skin peeling

Mild side effects

• Lower back pain
• joint pain
• abdominal pain
• neck pain
• weakness
• chest pain
• hypertension
• cardiovascular disease
• angina
• nausea

Store this medication in a tightly sealed container to protect it from air and moisture. It is best to keep it at room temperature, between 1 and 30 degrees Celsius.

Appearance

Light orange oval film-coated tablet

Package unit

4 tablets/PTP packaging