Medication info

Power Blue 5 Injection

Prescription medicationApproval withdrawn
Ingredient · strength
Zinc Sulfate Hydrate›Strength being verifiedCupric Sulfate Hydrate›Strength being verifiedManganese Sulfate Hydrate›Strength being verifiedChromic Chloride Hydrate›Strength being verifiedSelenious Acid›Strength being verified
Manufacturer / importer
대화제약(주)
Appearance
A colorless and transparent vial injection containing a colorless, odorless, or pale blue transparent liquid.
Packaging
10 mL vial × 10 pieces
Approval status
Approval withdrawn

MFDS item code 201605582 · Notified 2016.09.21

This product's status changed to Approval withdrawn on 2023.06.08. It may no longer be sold, so consult a doctor or pharmacist before taking it.

Summary

Main use
Improvement of nutritional status through trace element supply
Who uses it
Adults · Children
Adult dosage
Use according to physician's prescription, checking plasma trace element levels as a guideline for dose adjustment. For patients receiving metabolically stable non-oral nutritional solutions: Zinc 2.5-4mg per day, Copper 0.5-1.5mg per day, Manganese 0.15-0.8mg per day, Chromium 10-15㎍ per day, Selenium 20-40㎍ per day. Additionally, for metabolically stable patients with small bowel fluid loss: an additional 12.2mg/L (amount of small bowel fluid loss)
Children's dosage
- For pediatric patients under 5 years Zinc: 100㎍ per kg of body weight per day Copper: 20㎍ per kg of body weight per day Manganese: 2-10㎍ per kg of body weight per day Chromium: 0.14-0.20㎍ per kg of body weight per day Selenium:

Ingredients

Manufacturer
대화제약(주)

Efficacy & effects

Improvement of nutritional status through trace element supply

View approved original text

Administering trace elements such as zinc, copper, manganese, selenium, and chromium via intravenous nutrition helps to improve the nutritional status of patients and maintain normal metabolism and immune function. These trace elements play important roles in the body, and deficiencies can lead to various metabolic disorders or immunosuppression. Therefore, appropriate trace element supply during intravenous nutrition is essential for patient recovery and health maintenance.

Dosage and Administration

Adult dosage

Use according to physician's prescription, checking plasma trace element levels as a guideline for dose adjustment. For patients receiving metabolically stable non-oral nutritional solutions: Zinc 2.5-4mg per day, Copper 0.5-1.5mg per day, Manganese 0.15-0.8mg per day, Chromium 10-15㎍ per day, Selenium 20-40㎍ per day. Additionally, for metabolically stable patients with small bowel fluid loss: an additional 12.2mg/L (amount of small bowel fluid loss)

Children's dosage

- For pediatric patients under 5 years Zinc: 100㎍ per kg of body weight per day Copper: 20㎍ per kg of body weight per day Manganese: 2-10㎍ per kg of body weight per day Chromium: 0.14-0.20㎍ per kg of body weight per day Selenium:

Precautions

This medication contains benzyl alcohol, making it unsafe for use in premature or newborn infants. Direct intravenous injection without dilution can lead to phlebitis, so it must be diluted before use. It is a hypotonic solution, so it should only be used as a mixed injection and should not be administered alone. If toxic symptoms appear during administration, injection must be stopped immediately. Patients with impaired kidney function, especially premature infants, are at risk of toxicity due to aluminum accumulation, so caution is needed. The concentrations of trace elements such as zinc, copper, manganese, chromium, and selenium should be monitored periodically, and dosages should be adjusted accordingly. Renal failure patients may need to be cautious as zinc can accumulate in the body, and patients with biliary obstruction should be careful about copper and manganese accumulation. Diabetic patients should confirm the interactions of chromium with their current medications and condition as it can affect blood sugar control. Administration of this drug to pregnant women or women of childbearing potential should be decided carefully, taking potential risks and benefits into consideration. Overdosing may lead to toxic symptoms of zinc, copper, chromium, and selenium, so the prescribed dosage must be strictly followed. This medication should be used in a sterile condition, and before administration, it must be checked for discoloration or foreign substances. It should be stored in a sealed container to prevent air exposure, and it is best to maintain the storage temperature between 15 degrees and 30 degrees Celsius to preserve the drug's efficacy.

Side effects and when to seek care immediately

Serious side effects

  • Rapid breathing symptoms
  • phlebitis
  • hypotension
  • pulmonary edema
  • jaundice
  • decreased urine output
  • severe edema
  • increased blood pressure
  • diarrhea
  • decreased consciousness
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  • seizures
  • coma.

Mild side effects

  • Hyperhidrosis
  • blurred vision
  • tachycardia
  • hypothermia
  • diarrhea
  • vomiting
  • hair loss
  • nail weakness
  • dermatitis
  • dental damage
Show 13 more
  • gastrointestinal disturbance
  • irritability
  • depression
  • metallic taste
  • sweating
  • garlic-like smell during respiration
  • weakness
  • behavioral changes
  • glare
  • peripheral edema
  • nausea
  • ulcers
  • coma.

Not everyone experiences these, and they can vary from person to person.

Storage

This medication must be stored in a sealed container to prevent air exposure, and it is advisable to maintain the storage temperature between 15 degrees and 30 degrees Celsius. This helps to maintain the drug's effectiveness.

Appearance and packaging

Appearance

A colorless and transparent vial injection containing a colorless, odorless, or pale blue transparent liquid.

Package unit

10 mL vial × 10 pieces

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.