Dio V Plus Tablet 160/12.5 mg

Adult dose

The recommended adult dosage is one tablet of Valsartan 80 mg/Hydrochlorothiazide 12.5 mg once daily, taken with a small amount of water irrespective of meals. Valsartan 160 mg/Hydrochlorothiazide 12.5 mg is applied when prescribed for blood pressure lowering. No dosage adjustment is needed for patients with mild to moderate renal impairment. For patients with hepatic impairment, do not exceed 80 mg of Valsartan per day if they have mild to moderate hepatic impairment without cholestasis.

This medication can cause serious harm to the fetus if taken during pregnancy, especially in the second and third trimesters, and it should be discontinued immediately upon confirmation of pregnancy. Patients with allergies to this medication's ingredients or sulfonamide drugs should not use it. It is safer not to administer this medication to patients with severe liver or kidney dysfunction, or those with specific liver diseases. Caution should be exercised when using this medication in patients with unstable potassium levels or electrolyte disorders, as well as patients with electrolyte imbalances such as hyponatremia or hypokalemia. Particularly, elderly patients, those with heart disease, diabetes, and decreased kidney function should have their blood pressure and kidney function monitored frequently while taking this medication. This medication may cause dizziness or drowsiness; caution is needed when driving or operating machinery. Potassium supplements or potassium-containing foods should not be taken without consulting a physician, and it is crucial to regularly check serum potassium levels. The hydrochlorothiazide component may react sensitively to sunlight, so precautions such as UV protection and skin care should be taken while taking it. If blood pressure becomes too low or severe side effects occur while taking this medication, seek medical advice immediately. Additionally, this medication may interact with other drugs, so patients should inform healthcare providers of any other drugs they are taking. Safety in pediatric patients has not been established, so it is advisable not to use it in children. When storing, keep it out of reach of children and store it in its original container away from moisture.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, mucosal pain in the mouth/eyes, shortness of breath or difficulty breathing, asthma attack, respiratory abnormalities accompanied by cough and fever, jaundice indicated by yellowing of skin or eyes, extreme lethargy, sudden and severe headache, lightning headache, seizures, altered consciousness, visual disturbances, paralysis, urination

Mild side effects

• Headache
• dizziness
• nasopharyngitis
• fatigue
• back pain
• cough
• upper respiratory infection
• diarrhea
• joint pain
• abdominal pain

This medication should be stored in a sealed container to protect it from air and moisture and kept in a cool place below 30 degrees Celsius. Proper storage will help maintain the drug's efficacy for a longer period.

Appearance

Dark red oval film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle