Telmisartan 40 mg (Telmisartan)

Adult dose

For the treatment of essential hypertension, administer 40 mg of telmisartan orally once daily with water, without regard to meals. Depending on the patient, 20 mg once daily may be effective, and if necessary, it can be increased to 80 mg once daily. Dose increases show maximum blood pressure-lowering effects 4 to 8 weeks after treatment initiation. For reducing the risk of cardiovascular diseases, it is recommended to take 80 mg of this medication orally once daily with water, without regard to meals. There is no known risk reduction effect on morbidity and mortality from cardiovascular diseases at doses below 80 mg. When starting treatment with this medication for the purpose of cardiovascular risk reduction, monitoring blood pressure is recommended, and appropriate regulation of antihypertensives may be required. ○ Patients with liver impairment Caution is advised when administering to patients with mild to moderate liver impairment, and the dose should not exceed 40 mg once daily.

This medication can cause serious harm, especially to the fetus and newborn, during pregnancy, so it should be discontinued immediately upon confirmation of pregnancy. It should not be used in patients with an allergic reaction to this medication, during pregnancy, severe liver impairment, issues with bile excretion, a history of hereditary angioedema, or certain kidney diseases or diabetes. Elderly patients or those with high potassium levels, liver impairment, heart valve problems, cardiovascular diseases, gastrointestinal diseases, and renal vascular hypertension should use this medication cautiously. Various adverse reactions such as infections, blood abnormalities, allergies, hyperkalemia, hypoglycemia, neurological symptoms, cardiovascular abnormalities, gastrointestinal disorders, liver function abnormalities, skin rashes, myalgia, and decreased kidney function may occur while using this medication, and patients should consult a doctor immediately if symptoms appear. Particular attention should be paid to monitor for excessively low blood pressure, shock, fainting, or loss of consciousness, and serious side effects such as liver dysfunction, interstitial pneumonia, and rhabdomyolysis have also been reported. It is important to regularly monitor serum potassium and creatinine levels in patients with decreased kidney function, and patients with low blood volume or sodium may be at risk of hypotension and should have their condition improved before administration. Additionally, the effect of this medication may increase when used with other antihypertensives, and interactions may occur when combined with certain drugs; therefore, patients must inform their doctor or pharmacist about any other medications they are taking. It is advisable for women who are pregnant or breastfeeding to avoid using this medication; if it must be taken, they should consult a specialist and discontinue breastfeeding. It is not recommended for children under 18 years of age as safety and efficacy have not been established. In elderly patients, careful monitoring of their condition is essential to avoid excessively low blood pressure. In case of overdose, symptoms such as hypotension, abnormal heart rate, dizziness, and acute renal failure may occur, necessitating immediate appropriate treatment in a medical facility, as this medication is not removed by hemodialysis. This medication should be stored out of reach of children, and it is best to keep the packaging sealed until time of use.

Serious side effects

Urticaria, severe swelling (including angioedema), chest tightness, difficulty breathing, cold sweat, pallor, severe allergic reactions, severe rash with high fever, blisters, skin peeling, pain of mouth/eye mucosa, severe skin reactions, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough and fever, liver or biliary abnormalities (including liver dysfunction and jaundice), sudden and severe headaches, thunderclap headaches

Mild side effects

• Upper respiratory tract infections
• pharyngitis
• sinusitis
• urinary tract infections
• cystitis
• anemia
• thrombocytopenia
• eosinophilia
• hypersensitivity
• hyperkalemia

This medication should be stored in a tightly closed container to prevent exposure to air or moisture, at a temperature between 1 and 30 degrees Celsius. Storing it this way will maintain its efficacy and allow for safe use.

Appearance

White or almost white, round, biconvex tablets

Package unit

30 tablets/box [10 tablets/PTP x 3]