EzeSant 10/10 mg Tablet (Ezetimibe, Rosuvastatin)

Adult dose

This medication is administered once daily, regardless of meals. The dosage range is 10/5 mg to 10/20 mg once daily. A starting dose of 10/5 mg once daily is recommended. For patients requiring a greater reduction in LDL-cholesterol, the dosage may be adjusted. Following initiation of treatment or adjustment of dosage, lipid levels should be checked at least 4 weeks later before making any further dosage adjustments, with a maximum of 10/20 mg once daily.

This medication may cause severe muscle issues; therefore, if severe muscle pain or weakness occurs, consult a physician immediately. Patients with renal conditions or other risk factors should consult a physician before taking this medication as muscle damage can rapidly impair renal function. Patients allergic to any ingredients in this medication, those with liver disease, or those with severe renal impairment should not take this medication. Women who are pregnant, may become pregnant, or are breastfeeding should not take this medication and should use appropriate contraception during treatment. If there are abnormalities in liver function or significantly elevated liver enzyme levels, regular liver function tests should be performed before and during the use of this medication. This medication may interact with other drugs; patients taking other medications must inform their physician, particularly if anticoagulants, fibrates, certain antibiotics, or antifungals are being used concomitantly. Elderly patients or those at risk for myopathy should be monitored more carefully while on this medication, and if muscle pain or weakness occurs, inform medical staff immediately. Neurological symptoms such as dizziness or headaches may occur, so caution is advised when driving or operating machinery. The safety and efficacy of this medication have not been sufficiently proven in children, so it is not recommended for pediatric use. Store out of reach of children, and do not transfer to a different container.

Serious side effects

Urticaria, cold sweat, severe skin adverse reactions (Stevens-Johnson syndrome, drug reaction with eosinophilia and systemic symptoms), difficulty breathing, respiratory distress, chest tightness, severe swelling (edema, generalized edema), elevated blood pressure, renal dysfunction, renal failure, jaundice, hepatic toxicity, acute hepatitis, toxic hepatitis, severe allergic reactions, liver abnormalities (jaundice), severe neurological symptoms (headaches, dizziness, somnolence,

Mild side effects

• Nasopharyngitis
• arthralgia
• headaches
• dizziness
• upper respiratory infections
• myalgia
• constipation
• nausea
• abdominal pain
• acneiform dermatitis

This medication may be sensitive to air or moisture, so it should be stored in a sealed container. It is advisable to maintain a storage temperature between 1°C and 30°C. This will safely preserve the efficacy of the medication.

Appearance

Light pink, rectangular film-coated tablet

Package unit

30 tablets / box (10 tablets / PTP X 3)