Aclenthin Duo Syrup (Amoxicillin·Clavulanate Potassium (7:1))

Adult dose

For recurrent tonsillitis and upper respiratory infections, lower respiratory infections, urinary tract infections, and mild to moderate skin and soft tissue infections, the usual dosage is 25 mg/3.6 mg/Kg/day (as amoxicillin/clavulanate potassium) divided into two doses. For severe infections such as otitis media, sinusitis, lower respiratory infections such as bronchopneumonia, and urinary tract infections, the usual dosage is 45 mg/6.4 mg/Kg/day (as amoxicillin/clavulanate potassium) divided into two doses.

Child dose

The 7:1 syrup is not suitable for children under 2 months. Children with renal impairment are not suitable for the 7:1 syrup.

This medication contains penicillin-type antibiotics, so individuals with a history of allergic reactions to this drug or similar drugs should not use it. Patients with viral infections such as infectious mononucleosis or lymphocytic leukemia have a higher risk of rash and should avoid administration. Patients with a history of liver dysfunction or jaundice due to this medication or penicillin should not use it due to the risk of recurrence. This medication contains lactose, so it should not be administered to patients with lactose intolerance or galactose metabolism disorders. Patients with poor liver function or moderate to severe kidney function impairment should use it cautiously as the drug concentration may increase. Caution is advised for patients with a history of allergies, bronchial asthma, or symptoms such as urticaria. Patients with gastrointestinal symptoms such as vomiting or diarrhea should be careful as the drug may not be well absorbed. When taking this medication, consult a doctor immediately if symptoms such as diarrhea, abdominal pain, or bloody stool occur, as severe gastroenteritis or colitis may occur. Symptoms of liver dysfunction may rarely appear, so especially for the elderly or those taking it for a long time, liver function tests may be necessary. Skin rash, itching, and in severe cases serious skin reactions such as Stevens-Johnson syndrome may occur, requiring immediate cessation of administration upon symptom onset. Blood-related symptoms can also rarely occur, so if bleeding or anemia symptoms arise, medical evaluation is necessary. Symptoms of central nervous system abnormalities such as anxiety, confusion, or seizures may appear, and if such symptoms occur, they should be reported immediately. This medication may interact with other drugs; therefore, if taking other medications, it is essential to inform healthcare providers. Pregnant or breastfeeding women should consult a doctor and use it cautiously, especially during early pregnancy it is advisable to avoid it. Children and the elderly may have different physiological functions, so dosage and intervals should be monitored carefully. Regular liver, kidney function, and blood tests are recommended for safety during the course of the medication. This medication should be stored in a sealed container as it is sensitive to air and moisture. It is important to store it in a cool, dry place below 25 degrees Celsius to maintain its effectiveness.

Serious side effects

Urticaria, chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in mucous membranes of mouth/eyes, shortness of breath or difficulty breathing, asthma attack, respiratory disturbances accompanied by cough and fever, jaundice (yellowing of skin or eyes), extreme lethargy, sudden and severe headache, lightning headache, seizures, confusion of consciousness, visual disturbances, paralysis, significantly reduced urine output

Mild side effects

• Diarrhea
• pseudomembranous colitis
• dyspepsia
• stomatitis
• gastritis
• glossitis
• black hairy tongue
• nausea
• vomiting
• loss of appetite

This medication is sensitive to air and moisture, so it must be stored in a sealed container. Additionally, it is important to keep it in a cool, dry place below 25 degrees Celsius to maintain its effectiveness.

Appearance

A syrup that is a white or pale yellow powder to be dissolved before use.

Package unit

50 milliliters/bottle [50mL (5.5057g)/bottle], 500 milliliters/bottle [500mL (55.057g)/bottle]