Crovatin Tablets 5mg (Rosuvastatin Calcium)

Adult dosage

For adult patients with primary hypercholesterolemia, mixed hyperlipidemia, dysbetalipoproteinemia, etc., the medication can be taken at any time during the day, regardless of meals. The initial dose is 5 mg once daily, adjusted to a maintenance dose as needed. The maintenance dose is commonly 10 mg once daily, with most patients maintaining this dose; adjust based on LDL cholesterol levels and treatment goals at intervals of 4 weeks or longer, up to a maximum of 20 mg.

Children's dosage

For pediatric patients with heterozygous familial hypercholesterolemia (aged 10 to 17 years), administer 5 mg to 20 mg once daily, adjusted according to treatment goals. The dosage should be adjusted at intervals of 4 weeks or longer.

This medication should not be used in certain patients. For example, patients with allergies to any component of this drug, those with severely impaired liver function, patients with muscle disorders and severe kidney diseases should not be administered this medication. Moreover, women who are pregnant or breastfeeding and those of childbearing potential who do not use adequate contraception should consult a physician before taking this medication. This medication can affect liver function, hence patients with a history of liver disease or those who consume alcohol heavily should undergo regular liver function tests. If symptoms such as muscle pain or weakness occur, inform a physician immediately and discontinue treatment if necessary. This medication may increase blood concentrations when taken with certain drugs, raising the risk of muscle diseases, thus patients taking other medications should inform their physician or pharmacist. Women of childbearing potential should use effective contraceptive methods while on this medication, and discontinue its use immediately upon confirming pregnancy. Breastfeeding mothers should also avoid taking this medication. In the case of overdose, there is no specific antidote, so treatment must be symptomatic, with monitoring of liver function and muscle enzyme levels. During the use of this medication, dizziness or headaches may occur, so caution is advised when driving or operating machinery. Lastly, this medication contains lactose and may not be suitable for patients with lactose intolerance. Be sure to discuss any health conditions and other medications being taken with medical personnel before using this medication.

Serious side effects

Urticaria, hypersensitivity reactions including angioedema, severe swelling (edema), chest tightness, difficulty breathing, Stevens-Johnson syndrome, eosinophilia and systemic symptoms associated with drug reaction with eosinophilia and systemic symptoms (DRESS), jaundice, hepatitis, severe muscle weakness, ophthalmoplegia, thrombocytopenia, and rarely rhabdomyolysis, immune-mediated necrotizing myopathy, acute kidney failure, oliguria, memory loss, peripheral neuropathy, polyneuropathy, interstitial lung disease

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• muscle pain
• weakness
• diarrhea
• hematuria

This medication should be stored in a tightly closed container to prevent air and moisture entry, at a cool room temperature ideally between 1 and 30 degrees Celsius. This helps maintain the medication's effectiveness over time.

Appearance

Yellow round film-coated tablet

Package unit

28 tablets (14 tablets/Alu-Alu pack x 2), 30 tablets/bottle