Dituogel (Adapalene)

Adult dosage

Cleanse the affected area and dry it, then apply a thin layer to the acne-prone area before bedtime once daily, avoiding the eyes, lips, mucous membranes, and around the nose. If skin irritation occurs, reduce the number of applications (e.g., to once every two days) or discontinue treatment. Once the irritation subsides, the frequency of application can be increased or treatment resumed. Clinical improvement occurs after 4 to 8 weeks of treatment, and further improvement may be seen after 3 months.

This medication should not be used until patients with sunburn have completely recovered. It should not be used by individuals who are allergic to this drug or its components, pregnant women, women who may become pregnant, or in areas with damaged skin or specific skin diseases. Patients who are frequently exposed to sunlight or are sensitive to sunlight should exercise caution when using this medication, and it should also be used carefully by those with a history of allergies to the ingredients. Skin reactions such as dryness, irritation, burning sensation, and redness may occur during use, and these symptoms can improve by discontinuing treatment or reducing the frequency of application. If severe irritation or allergic reactions occur, discontinue or reduce the frequency of use, and if symptoms improve, it may be possible to resume once daily use. During treatment, avoid exposure to sunlight or artificial UV light, and when exposure occurs, wear sunscreen and protective clothing. It is advisable to stop using the medication on days with significant sun exposure. Increasing the amount of this medication will not produce faster results, and excessive use may worsen skin irritation. After using other exfoliating topical treatments, this medication should be used only after skin irritation has completely resolved. Once symptoms improve, it is advisable to discontinue the use of this medication and not to use it for prolonged periods. In the area where this medication is applied, do not use electrology, waxing, or chemical depilatories for hair removal. This medication is not significantly absorbed into the skin, which lowers the possibility of interactions with systemic drugs, but it is recommended not to use it with other retinoid drugs. It can be combined with other topical acne treatments if applied at different times, but should not be used together with strongly irritating cleansers or products with high chemical content. It should not be used during pregnancy, and if pregnancy is confirmed, treatment should be immediately discontinued. Caution is required if breastfeeding, and this medication should not be applied to the breast area. Safety and effectiveness in children under 12 years of age have not been established, thus its use is not recommended. In case of overdose or accidental ingestion, emergency measures such as gastric lavage may be necessary. This medication is for external use only and should be applied with care to avoid contact with eyes, mouth, nose, mucous membranes, or wounds. Keep out of reach of children and do not transfer to another container for safety. Based on experiences with similar medications, the risk of skin cancer may increase with exposure to sunlight or UV light, so it is important to minimize UV exposure.

Mild side effects

• Skin dryness
• skin irritation
• skin burning sensation
• redness
• contact dermatitis
• skin discomfort
• sunburn
• itching
• skin peeling
• acne

This medication should be stored in an airtight container and kept in a cool place below 25 degrees Celsius. Additionally, care should be taken not to freeze it.

Appearance

Translucent white gel

Package unit

10g/tube