Metformin and Sitagliptin Tablet 50/1000 mg

Adult dosage

This medication is generally taken twice daily with food, with a gradual increase in dosage to reduce gastrointestinal side effects caused by metformin. 1. Patients not currently treated with metformin: Take this medication 50/500 mg twice a day, one tablet at a time, and may increase to 50/1000 mg twice a day, one tablet at a time. 2. Patients currently receiving metformin:

This medication is used for the treatment of diabetes and helps to control blood sugar. Severe allergic reactions can occur during the use of this medication, so if symptoms such as skin rash, hives, difficulty breathing, or swelling of the face or neck occur, it should be stopped immediately and medical advice should be sought. There is a risk of serious pancreatic inflammation known as pancreatitis, so any symptoms including abdominal pain, nausea, vomiting, or fever should be reported to a healthcare professional immediately. Patients with poor kidney function or heart problems may face risks when taking this medication, so it must be used only after consulting with a doctor. The use of this medication should be temporarily stopped before and after examinations using iodine contrast agents, and resumption should only occur after confirming normal kidney function. It is safer for women who are pregnant or may become pregnant, as well as nursing mothers, to avoid this medication. Irregular meals, vigorous exercise, and concurrent use with certain medications can increase the risk of side effects such as hypoglycemia or lactic acidosis, requiring careful monitoring. This medication may cause gastrointestinal disturbances (diarrhea, nausea, vomiting, abdominal pain) and headaches, as well as cold symptoms. When taken with other antihyperglycemic agents, hypoglycemic symptoms may occur, thus blood sugar levels should be frequently monitored and dosage adjustments made as necessary. Lactic acidosis, a rare but very serious side effect, can happen; symptoms such as sudden muscle aches, shortness of breath, fatigue, or abdominal pain require immediate medical consultation. Long-term use of this medication may result in decreased Vitamin B12 levels, hence regular blood tests are recommended. Before surgery, this medication should be discontinued and restarted only after the patient's condition has stabilized. Elderly patients may have reduced kidney function, so regular kidney function monitoring and the lowest effective dose should be administered. In case of overdose, immediate medical care should be sought, and in some cases, blood dialysis may be necessary. Alcohol consumption during the use of this medication is best avoided, and any unusual symptoms associated with the medication should be discussed with a physician immediately.

Serious side effects

• Hives
• severe swelling (angioedema)
• chest tightness
• difficulty breathing
• anaphylaxis
• Stevens-Johnson syndrome
• severe skin reactions
• rash with fever
• blisters
• skin peeling

Mild side effects

• Diarrhea
• nausea
• vomiting
• abdominal pain
• upper respiratory infections
• nasopharyngitis
• headaches
• hypoglycemia
• constipation
• muscle pain

This medication should be stored in a sealed container that does not allow air to enter and kept at room temperature between 1 and 30 degrees Celsius. Storing it this way can maintain the medication's efficacy for a longer period.

Appearance

Dark red oval film-coated tablet

Package unit

Company packaging unit