Medication info

Almizojung

Prescription medicationTablet경구Approval withdrawn
Ingredient · strength
Ranitidine Hydrochloride›84mg / 1 tabletTripotassium Bismuth Dicitrate›100mg / 1 tabletSucralfate Hydrate›300mg / 1 tablet
Manufacturer / importer
주식회사제뉴원사이언스
Appearance
This medication is a round, white, film-coated tablet.
Packaging
30 tablets/bottle, 300 tablets/bottle
Approval status
Approval withdrawn

MFDS item code 201505441 · Approved 2015.08.07

This product's status changed to Approval withdrawn on 2025.01.20. It may no longer be sold, so consult a doctor or pharmacist before taking it.

Summary

Main use
Treatment of digestive diseases including gastric and duodenal ulcers, gastritis
Who takes it
Adults
Adult dose
Normally, take 2 tablets orally, twice a day, regardless of meals, in the morning and before bedtime. 1) Gastric and duodenal ulcers: Take 2 tablets, twice daily, or 4 tablets once daily at bedtime. Especially in cases of duodenal ulcers, taking 4 tablets twice a day in the morning and at bedtime can achieve a higher treatment rate. Used for ulcers caused by nonsteroidal anti-inflammatory medications or long-term use of nonsteroidal anti-inflammatory medications, the dosage remains the same. Typically, conditions induced by nonsteroidal anti-inflammatory medications heal within 8 weeks, although healing time may vary based on the patient. For recurrent ulcer patients who have demonstrated excellent effects with short-term therapy of this medication, a maintenance therapy of 2 tablets once daily before bedtime is recommended. 2) Gastroesophageal reflux disease: Take 2 tablets, twice daily for 8 weeks or 4 tablets once a day at bedtime. However, in cases of severe gastroesophageal reflux disease, the dosage may be increased to 4 tablets, four times a day. 3) Zollinger-Ellison syndrome: Start treatment with an initial dose of 2 tablets three times daily, with potential increments as needed. In severe cases, the physician may prescribe up to 6 g of ranitidine daily. 4) Peptic ulcer, acute stress ulcer, and upper gastrointestinal bleed due to acute mucosal lesions: Once oral administration is possible, transition from injection to oral dose of 2 tablets twice a day. 5) Pre-anesthetic medication (prevention of Mendelsohn's syndrome): Administer 2 tablets once, 2 hours prior to anesthesia induction. In this case, taking 2 tablets the night before surgery is also recommended.

Ingredients

Manufacturer
주식회사제뉴원사이언스

Efficacy & effects

Treatment of digestive diseases including gastric and duodenal ulcers, gastritis

  • Gastric ulcer
  • duodenal ulcer
  • gastritis
  • Zollinger-Ellison syndrome
  • gastroesophageal reflux disease
  • Mendelsohn's syndrome
  • postoperative ulcer
  • gastric ulcer due to NSAIDs
  • duodenal ulcer due to NSAIDs
View approved original text

This medication is used to treat digestive diseases such as gastric and duodenal ulcers, gastritis, and gastroesophageal reflux disease. It is also effective for conditions associated with excessive gastric acid secretion, such as Zollinger-Ellison syndrome. It is administered to prevent Mendelsohn's syndrome prior to anesthesia and aids in the prevention of postoperative ulcers. It is also used for the treatment of gastric and duodenal ulcers induced by nonsteroidal anti-inflammatory drugs (NSAIDs). Thus, it is used for the treatment and prevention of various gastrointestinal diseases.

How to take

Adult dose

Normally, take 2 tablets orally, twice a day, regardless of meals, in the morning and before bedtime. 1) Gastric and duodenal ulcers: Take 2 tablets, twice daily, or 4 tablets once daily at bedtime. Especially in cases of duodenal ulcers, taking 4 tablets twice a day in the morning and at bedtime can achieve a higher treatment rate. Used for ulcers caused by nonsteroidal anti-inflammatory medications or long-term use of nonsteroidal anti-inflammatory medications, the dosage remains the same. Typically, conditions induced by nonsteroidal anti-inflammatory medications heal within 8 weeks, although healing time may vary based on the patient. For recurrent ulcer patients who have demonstrated excellent effects with short-term therapy of this medication, a maintenance therapy of 2 tablets once daily before bedtime is recommended. 2) Gastroesophageal reflux disease: Take 2 tablets, twice daily for 8 weeks or 4 tablets once a day at bedtime. However, in cases of severe gastroesophageal reflux disease, the dosage may be increased to 4 tablets, four times a day. 3) Zollinger-Ellison syndrome: Start treatment with an initial dose of 2 tablets three times daily, with potential increments as needed. In severe cases, the physician may prescribe up to 6 g of ranitidine daily. 4) Peptic ulcer, acute stress ulcer, and upper gastrointestinal bleed due to acute mucosal lesions: Once oral administration is possible, transition from injection to oral dose of 2 tablets twice a day. 5) Pre-anesthetic medication (prevention of Mendelsohn's syndrome): Administer 2 tablets once, 2 hours prior to anesthesia induction. In this case, taking 2 tablets the night before surgery is also recommended.

Precautions

This medication should not be used in patients receiving dialysis. Patients who have had allergic reactions to this medication or its components should avoid taking it. This medication should not be used in patients with a history of acute porphyria as it may provoke seizures. It is safe to avoid this medication in patients with poor kidney function. This medication is not suitable for patients who have undergone gastrointestinal surgery. Women who are pregnant or may become pregnant should not take this medication. The safety of this medication has not been confirmed in premature infants or newborns, so it is not used in these populations. Patients on a diet that restricts potassium intake should be cautious when taking this medication. Patients with poor liver function should use this medication carefully, and those with a history of allergies should be cautious as well. Elderly individuals are at higher risk of side effects when using this medication, so caution is warranted. Patients with a past history of kidney disease should be monitored closely while taking this medication. When taken with nonsteroidal anti-inflammatory drugs, there is a risk of gastrointestinal bleeding, particularly in the elderly or in those with a history of gastric ulcers, who should undergo regular testing. This medication may mask symptoms of gastric cancer, so gastric ulcer patients or middle-aged individuals with recent digestive issues should confirm the possibility of cancer before taking it. Patients with gastric and duodenal ulcers infected with Helicobacter pylori should also receive treatment to eliminate this bacterium. Care must be taken when administering this medication to severely ill patients in intensive care, as it may lead to the formation of gastric stones. Patients with hypophosphatemia should be careful, as the aluminum component of this medication may interfere with phosphate absorption. Patients who have difficulty swallowing are at risk of developing respiratory complications after taking this medication, so caution is advised. During the use of this medication, severe allergic reactions or shock may rarely occur, so if any unusual symptoms appear, discontinue immediately and consult healthcare professionals. If symptoms of hypersensitivity such as skin rash, hives, or difficulty breathing occur, stop using the medication immediately. A rare side effect may include a decrease in blood cell counts, so if any symptoms of fatigue or bleeding arise, a blood test should be done. Symptoms of liver dysfunction can occur, so if jaundice or fatigue develops, discontinue use. Circulatory system issues such as arrhythmias or vasculitis have been reported rarely, warranting caution if symptoms arise. Gastrointestinal symptoms such as nausea, vomiting, diarrhea, and abdominal pain may occur but are generally mild. Central nervous system side effects such as dizziness, drowsiness, and confusion may rarely occur, so caution is warranted. Muscle aches or joint pain may occur rarely, and in severe cases, the medication should be discontinued. Symptoms such as skin rash or hair loss have been reported rarely, so any unusual symptoms should be consulted with healthcare professionals. It is advisable not to use this medication for prolonged periods, and it should be used at the minimum effective dose while regularly monitoring treatment progress. Elderly patients or those with chronic diseases are at increased risk of infections such as pneumonia, so caution is warranted. If dizziness or drowsiness occurs during use, avoid driving or operating dangerous machinery. This medication may interact with other drugs, so inform healthcare professionals if taking other medications. Regular blood tests are necessary, especially when used with drugs affecting blood coagulation. Certain antibiotics or anticonvulsants should be taken at staggered intervals when used with this medication, as it may affect drug absorption. Women who are pregnant or breastfeeding should avoid this medication, as its safety has not been established. The safety and efficacy in infants have not been sufficiently confirmed, so it is not recommended for use in children. This medication may cause false positives in some tests, so inform healthcare professionals about its use during examinations. In cases of overdose, appropriate treatment such as vomiting or gastric lavage is necessary, and blood dialysis may also be used for removal. This medication may reduce gastric acid secretion, increasing the risk of bacterial proliferation in the gastrointestinal tract, so caution with infections is needed. Long-term use may cause ocular issues, so regular ophthalmological check-ups are recommended.

Side effects and when to seek care immediately

Serious side effects

  • Hives
  • angioedema
  • shock (anaphylactic shock)
  • severe swelling (angioedema)
  • chest tightness (chest pain)
  • difficulty breathing (bronchospasm)
  • skin rash
  • severe rash with fever
  • blistering
  • skin peeling
Show 10 more
  • mucosal pain in mouth/eyes
  • liver abnormalities (jaundice)
  • hepatitis
  • altered consciousness
  • seizures
  • vision disturbances
  • paralysis
  • decreased urine output
  • severe swelling
  • increased blood pressure

Mild side effects

  • Skin rash
  • hives
  • angioedema
  • fever
  • bronchospasm
  • hypotension
  • chest pain
  • nausea
  • vomiting
  • constipation
Show 28 more
  • diarrhea
  • abdominal bloating
  • abdominal pain
  • loss of appetite
  • dizziness
  • drowsiness
  • confusion
  • excitement
  • insomnia
  • headache
  • heaviness
  • malaise
  • anxiety
  • mental confusion
  • depression
  • hallucinations
  • blurred vision
  • involuntary motor disturbances
  • gynecomastia
  • galactorrhea
  • erectile dysfunction
  • decreased libido
  • joint pain
  • muscle pain
  • itching
  • glossitis
  • alopecia
  • polymorphism

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in an airtight, sealed container, preferably at room temperature between 1°C and 30°C. Storing it this way can help maintain the efficacy of the medication for a longer period.

Appearance and packaging

Appearance

This medication is a round, white, film-coated tablet.

Package unit

30 tablets/bottle, 300 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.