SRB Tablet

Adult dose

Generally, 2 tablets should be taken orally twice a day in the morning and before bedtime, regardless of meals. 1) Gastric and duodenal ulcers: 2 tablets twice a day or 4 tablets once a day before bedtime. In particular, duodenal ulcer patients may take 4 tablets twice a day in the morning and before bedtime. 2) Gastroesophageal reflux disease: Take 2 tablets twice a day for 8 weeks or 4 tablets once a day before bedtime.

This medication should not be used in patients undergoing dialysis or with severely impaired kidney function. Additionally, it should not be administered to patients who have had allergic reactions to this drug or its components, have a history of acute porphyria, have undergone upper gastrointestinal surgery, are pregnant or may become pregnant, are premature infants or neonates, or are on a potassium-restricted diet. Caution is advised when administering this drug to patients with impaired liver function or a history of drug allergy, elderly patients, or those with a history of kidney dysfunction. If taking non-steroidal anti-inflammatory drugs, especially elderly patients or those with a history of peptic ulcer, should be monitored regularly. This medication may mask symptoms of gastric cancer; thus, patients over middle age with gastric ulcers or newly developed or changed dyspeptic symptoms should verify that they do not have a malignant disease before using it. Patients with Helicobacter pylori-positive gastric or duodenal ulcers require eradication therapy. In severe ICU patients, there is a risk of gastric stone formation, so caution is necessary, and patients with hypophosphatemia should be cautious as the aluminum component of this medication may hinder phosphate absorption. Patients with swallowing difficulties have also been reported to experience respiratory complications after taking this drug, so caution is needed. While taking this medicine, serious allergic reactions such as anaphylactic shock can rarely occur, so if symptoms appear, patients must stop taking the medication immediately and seek medical assistance. Adverse reactions such as skin rash, urticaria, angioedema, fever, bronchospasm, hypotension, and chest pain may occur, and if such symptoms occur, administration should be discontinued. Blood tests may show rare occurrences of leukopenia, thrombocytopenia, or abnormalities in liver function, and if symptoms present, testing should be conducted, and administration should be stopped if necessary. Abnormal heart rhythms, gastrointestinal symptoms (nausea, vomiting, constipation, diarrhea), and neurological symptoms (dizziness, drowsiness, confusion, convulsions) have also been reported, and healthcare professionals should be consulted in case of any abnormal symptoms. Rarely, symptoms such as myalgia, arthralgia, skin rashes, hair loss, stomatitis, and skin itching may occur. It is advisable not to take this medication for prolonged periods, and during treatment, regular blood tests and liver and kidney function tests should be performed to monitor any abnormalities. Elderly patients, those with chronic pulmonary diseases, diabetes, and patients with compromised immune systems may have an increased risk of pneumonia when taking this medication, so caution is needed. If dizziness or drowsiness occurs after taking the medication, it is advisable to avoid driving or operating machinery. This medication may interact with other drugs, so especially when taken with anticoagulants or certain antibiotics, anticonvulsants, it is important to inform healthcare providers, and dose adjustments or adjustments in administration intervals may be required. If sucralfate is included, it may interfere with the absorption of some antibiotics or other medications, so it is advisable to have an interval of at least 2 hours between administrations. Women who are pregnant or may become pregnant should not use this medication, and nursing mothers should also avoid it as the drug may be passed through breast milk. The safety and efficacy of this medication in children have not been established, so it is preferable not to use it in children. This drug may cause false positive results in urine protein tests, so it is recommended to use the sulfosalicylic acid method when conducting urine protein tests. In case of overdose, emergency measures such as vomiting or gastric lavage may be needed, and in severe cases, blood dialysis may be required. This medication may reduce gastric acid secretion and increase the proliferation of bacteria in the gastrointestinal tract, thus requiring periodic examinations, including eye examinations, during long-term use.

Serious side effects

Urticaria, angioedema, shock, anaphylactic shock, severe swelling (edema), chest pain due to hypersensitivity, hypotension, bronchospasm, angioedema, liver abnormalities (including hepatitis and jaundice), pancytopenia, acquired immune hemolytic anemia, liver dysfunction, arrhythmias (tachycardia, bradycardia, heart block, premature ventricular contractions), vasculitis, altered consciousness, convulsions, muscle cramps, rhabdomyolysis, severe neurological symptoms (severe headache, convulsions)

Mild side effects

• Skin rash
• urticaria
• angioedema
• fever
• bronchospasm
• hypotension
• chest pain
• granulocytopenia
• leukopenia
• thrombocytopenia

This medication should be stored in a tightly sealed container to prevent air exposure and kept at a temperature between 1°C and 30°C at room temperature. Proper storage will help maintain the effectiveness of the medication.

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 500 tablets/bottle