Glupen M Tablet

Adult dose

This medication is administered 1-2 times daily before meals or with meals. The dosage can be adjusted based on each patient's current treatment regimen, efficacy, and tolerance, for which appropriate blood sugar monitoring should occur. Typically, treatment is initiated at a low dose, with adjustments based on the current medications and blood glucose levels. In clinical trials, the initial daily dose was Glimperide/Metformin Hydrochloride

This medication can cause severe lactic acidosis or hypoglycemia, and caution is necessary. Particularly, if renal function declines rapidly, the drug may accumulate in the body and increase risk, so renal function should be monitored regularly. If symptoms of dehydration, severe diarrhea, vomiting, or fever occur, temporarily discontinuing the medication and consulting a physician is advised. Additionally, caution is required when taken with other medications that could affect renal function. During treatment, excessive alcohol consumption should be avoided, and patients with impaired liver function should not use this medication. There may be risks for cardiovascular diseases, so monitoring heart health status before and after treatment is important. Pregnant or breastfeeding women should avoid taking this medication and switch to alternative treatments if necessary. Special caution is needed for children or elderly patients, as safety and efficacy are not sufficiently proven. Patients should be aware of symptoms of hypoglycemia during treatment and take immediate appropriate action if symptoms arise. This medication may cause gastrointestinal discomfort, skin rash, or blood abnormalities; if any unusual symptoms occur, consult a physician. It is also important to regularly monitor the effects of the medication through blood tests and kidney function tests. Overdose can lead to serious side effects such as hypoglycemia or lactic acidosis, requiring immediate medical attention. Caution is advised while driving or operating machinery due to potential diminished alertness from hypoglycemia or other side effects. Store the medication out of reach of children and avoid transferring it to other containers.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor → severe allergic reaction. High fever with severe rash, blisters, skin peeling, mucosal pain in mouth/eyes → severe skin reaction. Shortness of breath or difficulty breathing, asthma attack, cough + fever with breathing abnormalities → respiratory issues. Skin or eyes turning yellow (jaundice), extreme fatigue → liver abnormalities (jaundice). Sudden and

Mild side effects

• Nausea
• vomiting
• abdominal distension
• loss of appetite
• dyspepsia
• constipation
• abdominal pain
• metallic taste
• visual impairment
• erythema

This medication should be stored in a tightly sealed container that allows for air circulation, ideally at room temperature between 1 and 30 degrees Celsius. This storage method helps to maintain the medication's efficacy over time.

Appearance

White rectangular film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle