Lovastatin 10 mg Tablet (Rosuvastatin Calcium)

Adult dose

Can be taken any time of day, regardless of meals. The initial dose is 5 mg once daily, and the maintenance dose is typically 10 mg once daily, with most patients adjusting at this dosage. The maintenance dose should be appropriately adjusted based on LDL cholesterol levels, treatment goals, and the patient's response, with a maximum daily increase up to 20 mg if necessary, spaced at least 4 weeks apart.

Child dose

For pediatric patients with heterozygous familial hypercholesterolemia (ages 10 to 17), administer a dose between 5 mg and 20 mg once daily. The dosage should be adjusted based on the individual patient's treatment goals, usually every 4 weeks.

This medication should not be used in certain patients. For example, patients with allergies to any component of this medication, severely impaired liver function, muscle diseases, severe renal impairment, or pregnant or breastfeeding women should not take this medication. Additionally, caution should be exercised in patients at high risk of muscle-related side effects or those taking certain medications concurrently. This medication may affect liver function, so patients with a history of liver disease or those who consume alcohol heavily should regularly undergo liver function tests. If symptoms such as muscle pain, weakness, or damage occur, the doctor should be notified immediately, and in severe cases, discontinuation of the medication may be necessary. This medication may cause elevated blood sugar levels in some patients, so those at risk for diabetes should periodically monitor their blood sugar. This medication may reach higher concentrations in patients with specific genotypes, requiring dosage adjustment if side effects occur during treatment. Furthermore, this medication can interact with other drugs, so if other medications are being taken, it is essential to inform healthcare professionals. Care should be taken when using with some antiviral agents, antibiotics, immunosuppressants, and fibrate medications. Women of childbearing potential should use appropriate contraception while on this medication, and if pregnancy is confirmed, it should be stopped immediately. Breastfeeding women are also advised against using this medication. In case of overdose, there is no specific antidote, so treatment should be symptomatic, and liver and muscle function tests are necessary. Finally, this medication may cause dizziness or other symptoms, so caution is advised when driving or operating machinery.

Serious side effects

• Hypersensitivity reactions including hives and angioedema
• Severe allergic reactions
• Severe rash with high fever, blisters, peeling skin, pain in mouth/eyes
• Stevens-Johnson syndrome
• Drug reaction with eosinophilia and systemic symptoms (DRESS)
• Difficulty breathing, dyspnea, respiratory issues
• Yellowing of skin or eyes (jaundice), hepatitis, liver dysfunction
• Severe liver damage and/or high bilirubinemia or jaundice
• Severe

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• muscle pain
• weakness
• hematuria
• diarrhea

This medication should be stored in a tightly closed container to prevent exposure to air and moisture, ideally at room temperature between 1 to 30 degrees Celsius. This will help maintain the medication's effectiveness.

Appearance

Pink round film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle