Rosuko Tablet 20mg (Rosuvastatin Calcium)

Adult dosage

The initial dose is 5mg once daily, and if a greater reduction in LDL cholesterol is necessary, it can be adjusted to a maintenance dose. The maintenance dose is typically 10mg once daily, with most patients managed at this dose. The maintenance dose should be adjusted appropriately based on LDL cholesterol levels, therapeutic goals, and the patient's response, with a maximum daily dose of 20mg.

Children's dosage

The usual dosage range for pediatric patients with heterozygous familial hypercholesterolemia (ages 10 to 17) is 5mg to 20mg once daily. The dosing should be adjusted according to the individual patient's therapeutic goals.

This medication should not be administered to certain patients. For example, patients who are allergic to this medication, those with severely impaired liver function, patients with muscle disorders, severely impaired kidney function, and pregnant or breastfeeding women should not use this medication. Additionally, women of childbearing potential should only take this medication if they are unlikely to become pregnant and must use appropriate contraceptive methods. This medication can cause muscle-related side effects; therefore, if symptoms of muscle pain or muscle weakness occur, patients must inform their doctor immediately. In particular, patients with reduced kidney function or a history of hypothyroidism or genetic muscle diseases should exercise extra caution. There may be abnormal liver function; hence, patients with a history of liver disease or those consuming alcohol excessively should have regular liver function tests. Concurrently taking this medication with some other medications may increase blood concentrations, thus raising the risk of muscle damage; always consult with a doctor when taking other medications together. Pregnant or breastfeeding women should not take this medication, and women who may become pregnant must use appropriate contraceptive methods. During the course of this medication, blood sugar levels may occasionally rise, so patients at risk for diabetes should regularly monitor their blood sugar levels. In cases of overdose, there is no specific antidote; therefore, treatment should be based on symptoms, while monitoring liver function and muscle enzyme levels. This medication may cause symptoms such as dizziness, so caution is advised when driving or operating machinery. Lastly, if severe rash or allergic reactions occur during the use of this medication, it must be stopped immediately, and medical attention should be sought.

Serious side effects

Allergic reactions including urticaria and angioedema, Stevens-Johnson syndrome, eosinophilia and systemic symptoms associated drug reaction syndrome, jaundice, hepatitis, fatal and non-fatal hepatic failure, rhabdomyolysis, immune-mediated necrotizing myopathy, acute kidney injury, anuria, dyspnea, interstitial lung disease

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• rash
• myalgia
• weakness
• diarrhea

This medication may be sensitive to air and moisture, so it must be stored in a tightly closed container. It is recommended to keep it at room temperature between 1 degree and 30 degrees Celsius. This helps maintain the drug's efficacy over time.

Appearance

Brown round film-coated tablets

Package unit

28 tablets (7 tablets/ Alu-Alu x 4)