Exipium Tablets 20 mg (Esomeprazole Magnesium Trihydrate)

Adult dosage

This medication should be swallowed with liquids such as water and should not be chewed or crushed. 1. Gastroesophageal Reflux Disease (GERD) - Treatment of erosive esophagitis: 40 mg once daily for 4 weeks - If esophagitis is untreated or symptoms persist, continue for 4 more weeks - Maintenance therapy for preventing recurrent esophagitis: 20 mg once daily - Treatment of GERD symptoms without esophagitis: 1

Children's dosage

Adolescents aged 12 and older - Treatment of erosive esophagitis: 40 mg once daily for 4 weeks - If esophagitis is untreated or symptoms persist, continue for 4 more weeks - GERD symptoms without esophagitis

This medication should not be used in certain patients. Patients who have had an allergy or hypersensitivity reaction to this medication or any of its components, as well as those allergic to penicillin or macrolide antibiotics, should not be administered this drug. Patients taking certain medications (terfenadine, cisapride, pimodi, astemizole, atazanavir, nelfinavir, etc.), nursing mothers, and patients with a history of myocardial infarction should also avoid using this medication. This drug contains the dye Yellow No. 4; therefore, patients with a history of allergy to this component should use it cautiously. While taking this medication, various adverse reactions may occur, so caution is necessary. Gastrointestinal symptoms such as headache, abdominal pain, diarrhea, constipation, nausea, and vomiting may occur, along with skin rashes, itching, and occasionally severe skin reactions. Blood abnormalities, hypomagnesemia, neurological symptoms, and liver function anomalies have also been reported. Regular check-ups are necessary when this drug is used for long periods, and patients should consult their doctor if symptoms change. Particular caution is advisable for long-term use beyond one year due to the potential increased risk of fractures and occurrence of hypomagnesemia. This medication interacts with many other drugs, which may alter blood concentration depending on what else is taken. Careful monitoring is advised when co-administered with antibiotics, antiviral medications, anticoagulants, and antiepileptics as per doctor’s guidance. Information regarding safety while pregnant or nursing is limited; therefore, a careful decision should be made after consulting with a doctor if necessary. In case of an overdose, there is no specific antidote, so management should be symptom-related, and it should be kept out of children's reach. Additionally, transferring the medication to another container is not advisable as it may negatively affect quality.

Serious side effects

Urticaria, angioedema, anaphylactic reactions, shock, angioedema, fever, severe hypomagnesemia, hypocalcemia, hypokalemia, hepatitis, jaundice, liver failure, encephalopathy, mucocutaneous hypersensitivity syndrome (Stevens-Johnson syndrome), toxic epidermal necrolysis (Lyell syndrome), acute generalized exanthematous pustulosis, drug reaction with eosinophilia and systemic symptoms (DRESS syndrome), interstitial nephritis, severe cutaneous adverse reactions, severe allergies

Mild side effects

• Headache
• insomnia
• anxiety
• mental confusion
• depression
• aggression
• hallucinations
• dizziness
• drowsiness
• taste disorders

This medication should be stored in a tightly sealed container to prevent exposure to air and moisture. It is recommended to store it at room temperature between 1 degree and 30 degrees Celsius.

Appearance

Pale pink round film-coated tablets

Package unit

28 tablets (14 tablets/PTP x 2)