Medication info
Megaset Semi Tablet

Megaset Semi Tablet

Prescription medicationTablet경구
Ingredient · strength
Acetaminophen›162.5mg / 1 tabletTramadol Hydrochloride›18.75mg / 1 tablet
Manufacturer / importer
대화제약(주)
Appearance
Pale yellow oblong film-coated tablet
Packaging
30 tablets/bottle, 300 tablets/bottle
Approval status
Active

MFDS item code 201402450 · Approved 2014.05.29 · Insurance code 645604410

Summary

Main use
Relief of moderate to severe acute and chronic pain
Who takes it
Adults · Children
Adult dose
Administer 4 tablets as an initial dose, followed by a dosing interval of at least 6 hours. Do not exceed 16 tablets in one day. For elderly patients, administer the usual adult dosage, and for those over 75, the interval should be at least 6 hours. For patients with moderate renal impairment, extend the dosing interval to 12 hours. Do not administer to patients with severe renal or hepatic impairment.
Child dose
Children over 12 years of age should adjust the dose according to the level of pain and therapeutic response similar to adults. The initial dose is 4 tablets, and the dosing interval should be at least 6 hours. Do not exceed 16 tablets in one day.

Ingredients

Manufacturer
대화제약(주)

Efficacy & effects

Relief of moderate to severe acute and chronic pain

  • Moderate pain
  • severe pain
  • acute pain
  • chronic pain
View approved original text

This medication is used to relieve acute and chronic pain ranging from moderate to severe.

How to take

Adult dose

Administer 4 tablets as an initial dose, followed by a dosing interval of at least 6 hours. Do not exceed 16 tablets in one day. For elderly patients, administer the usual adult dosage, and for those over 75, the interval should be at least 6 hours. For patients with moderate renal impairment, extend the dosing interval to 12 hours. Do not administer to patients with severe renal or hepatic impairment.

Child dose

Children over 12 years of age should adjust the dose according to the level of pain and therapeutic response similar to adults. The initial dose is 4 tablets, and the dosing interval should be at least 6 hours. Do not exceed 16 tablets in one day.

Precautions

This medication can put strain on the liver, so individuals who consume more than three alcoholic drinks daily should consult a doctor or pharmacist before taking it. When taking this medication, severe rashes, blisters, or allergic reactions may occur on the skin. In such cases, the medication should be discontinued immediately, and medical assistance should be sought. There is a risk of seizures when taking this medication, so caution is advised for those with a history of seizures or when taken with certain antidepressants or narcotic analgesics. In patients with acute asthma who have difficulty breathing, the use of this medication may be dangerous and should only be administered in a monitored medical environment. Taking this medication in conjunction with alcohol or central nervous system depressants can cause severe drowsiness, respiratory depression, and coma; therefore, such combinations should be avoided or strictly monitored by healthcare professionals. Patients with head injuries or elevated intracranial pressure should be cautious, as this medication may worsen symptoms due to respiratory depression. This medication can cause physical and psychological dependence, so careful monitoring of potential dependency is necessary with long-term use. Patients with poor liver function or liver disease should consult a doctor before taking this medication and should be careful not to exceed the recommended dosage. It is particularly safe to avoid administering this medication to children under 12 years of age and adolescents under 18 years who have undergone tonsillectomy or adenoidectomy. It may cause sleep apnea or hypoxia, so if such symptoms occur or worsen, consider reducing or discontinuing the medication. Electrolyte disturbances such as hyponatremia may occur, so elderly patients or those with risk factors should be closely monitored for symptoms. Pregnant or breastfeeding women should be aware that this medication can affect the fetus or newborn, so they should consult a healthcare provider. It is advisable to avoid use while breastfeeding. Drowsiness or dizziness may occur when driving or operating machinery, so caution is necessary during such activities. Overdose can lead to serious side effects such as respiratory depression, seizures, and liver damage, so it is crucial to adhere to the recommended dosage and not exceed it. This medication can interact with various drugs, so if you are taking other medications, be sure to inform your doctor or pharmacist and exercise caution when using them together.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in the oral/ocular mucosa, difficulty breathing or shortness of breath, asthma attack, respiratory issues accompanied by cough + fever, jaundice (yellowing of the skin or eyes), extreme lethargy, sudden severe headache, lightning headache, seizures, altered consciousness, vision changes, paralysis, urination

Mild side effects

  • Decreased appetite
  • insomnia
  • depression
  • dizziness
  • headache
  • drowsiness
  • nausea
  • vomiting
  • constipation
  • dry mouth
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  • diarrhea
  • indigestion
  • abdominal pain
  • abdominal discomfort
  • flatulence
  • pruritus
  • sweating
  • rash
  • fatigue
  • flushing
  • anxiety
  • neuroticism
  • emotional instability
  • euphoria
  • decreased libido
  • sleep disturbances
  • confusion
  • disorientation
  • agitation
  • abnormal dreams
  • drug abuse
  • hallucinations
  • withdrawal syndrome
  • migraine
  • somnolence
  • sensory loss
  • tremors
  • paresthesia
  • attention deficit

Not everyone experiences these, and they can vary from person to person.

Storage

Store this medication in a tightly sealed container to protect it from air and moisture, and keep it at room temperature between 1 and 30 degrees Celsius. Proper storage helps maintain the effectiveness of the medication for a longer period.

Appearance and packaging

Appearance

Pale yellow oblong film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

No questions yet.

For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.