Medication info
Gyeongbora Rabeprazole Tablet 20 mg (Rabeprazole Sodium)

Gyeongbora Rabeprazole Tablet 20 mg (Rabeprazole Sodium)

Prescription medicationTablet경구
Ingredient · strength
Rabeprazole Sodium›20mg / 1 tablet
Manufacturer / importer
(주)경보제약
Appearance
Pale yellow, round, enteric-coated tablet
Packaging
28 tablets (14 tablets/AluAlu packaging x 2)
Approval status
Active

MFDS item code 201308942 · Approved 2013.08.22 · Insurance code 665001780

Summary

Main use
Treatment of gastric ulcers and duodenal ulcers, alleviation of gastroesophageal reflux disease symptoms, and maintenance therapy effects
Who takes it
Adults
Adult dose
For gastric ulcers and duodenal ulcers: Administer 10 mg orally once daily, and based on symptoms, it can be increased to 20 mg once daily. Treatment duration is up to 8 weeks for gastric ulcers and up to 6 weeks for duodenal ulcers. For erosive or ulcerative gastroesophageal reflux disease: Administer 10 mg or 20 mg once daily for 4-8 weeks. If symptoms persist after 8 weeks of treatment, an additional course of 10 mg or 20 mg, taken twice daily for another 8 weeks, may be considered.

Ingredients

Manufacturer
(주)경보제약

Efficacy & effects

Treatment of gastric ulcers and duodenal ulcers, alleviation of gastroesophageal reflux disease symptoms, and maintenance therapy effects

  • Gastric ulcers
  • duodenal ulcers
  • erosive gastroesophageal reflux disease
  • ulcerative gastroesophageal reflux disease
  • symptoms of gastroesophageal reflux disease
  • gastrointestinal ulcers
  • Zollinger-Ellison syndrome
View approved original text

This medication is used to treat gastric ulcers, duodenal ulcers, erosive and ulcerative gastroesophageal reflux disease. It alleviates the symptoms of gastroesophageal reflux disease and is also helpful for long-term maintenance therapy for this condition. Additionally, it can be used with antibiotics for patients with gastrointestinal ulcers infected with Helicobacter pylori to enhance therapeutic effects. It is also indicated for the treatment of Zollinger-Ellison syndrome. Therefore, it is used as an effective agent for various gastrointestinal diseases.

How to take

Adult dose

For gastric ulcers and duodenal ulcers: Administer 10 mg orally once daily, and based on symptoms, it can be increased to 20 mg once daily. Treatment duration is up to 8 weeks for gastric ulcers and up to 6 weeks for duodenal ulcers. For erosive or ulcerative gastroesophageal reflux disease: Administer 10 mg or 20 mg once daily for 4-8 weeks. If symptoms persist after 8 weeks of treatment, an additional course of 10 mg or 20 mg, taken twice daily for another 8 weeks, may be considered.

Precautions

This medication should not be used in patients with an allergic reaction or hypersensitivity to certain ingredients. In particular, it should be avoided in patients hypersensitive to penicillin or macrolide antibiotics, pregnant or nursing women, and patients taking certain antivirals (atazanavir, rilpivirine). Patients with liver function issues, elderly patients, those with a history of drug allergies, and those sensitive to the dye contained in this medicine (Yellow No. 4) should use it cautiously. While taking this medication, various side effects such as skin rash, itching, blood disorders, liver dysfunction, heart issues, gastrointestinal abnormalities, neurological symptoms, respiratory problems, muscle and joint pain, skin abnormalities, visual and auditory disturbances, and urinary issues may occur, so any abnormal symptoms should be promptly consulted with healthcare personnel. This medication suppresses gastric acid secretion, and long-term use may increase the risk of gastrointestinal infections and the risk of fractures associated with osteoporosis. Therefore, regular examinations are necessary during prolonged use. Moreover, this medication can interact with other drugs; caution is required when used in combination with warfarin, methotrexate, certain antibiotics, and antivirals, and you must inform healthcare personnel about any other medications being taken. Pregnant or nursing women should not use this medication, and elderly patients should exercise caution as they may have a higher risk of side effects due to decreased liver function. Do not chew or crush this medication; swallow the tablet whole and keep it out of reach of children. In the case of overdose, there is no specific antidote, so treatment should be symptomatic and supportive, and immediate medical assistance should be sought if abnormal symptoms appear.

Side effects and when to seek care immediately

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in oral/eye mucosa, shortness of breath or difficulty breathing, asthma attacks, respiratory issues accompanied by cough and fever, jaundice (yellowing of the skin or eyes), extreme lethargy, sudden severe headache, lightning-like headaches, seizures, confusion of consciousness, visual disturbances, paralysis, urination

Mild side effects

  • Rash
  • urticaria
  • itching
  • decreased red blood cells
  • decreased white blood cells
  • increased white blood cells
  • eosinophilia
  • neutrophilia
  • decreased lymphocytes
  • anemia
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  • petechiae
  • lymphadenopathy
  • hypochromic anemia
  • pancytopenia
  • agranulocytosis
  • thrombocytopenia
  • hemolytic anemia
  • elevated ALT
  • elevated AST
  • elevated ALP
  • elevated γ-GTP
  • elevated LDH
  • elevated total bilirubin
  • hypertension
  • myocardial infarction
  • ECG abnormalities
  • migraine
  • syncope
  • angina
  • heart block

Not everyone experiences these, and they can vary from person to person.

Storage

This medication may be sensitive to air and moisture, so it should be stored in a tightly closed container. The storage temperature should be maintained at room temperature between 1 degree and 30 degrees Celsius to preserve the drug's efficacy and safety for a prolonged period.

Appearance and packaging

Appearance

Pale yellow, round, enteric-coated tablet

Package unit

28 tablets (14 tablets/AluAlu packaging x 2)

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.