Olmeact Tablet 40 mg (Olmesartan Medoxomil)

Adult dose

The recommended initial dose for adults is 10 mg once daily, administered regardless of meals. If blood pressure is not adequately controlled at this dose, it may be increased to 20 mg once daily, and if additional blood pressure reduction is needed, the dose may be increased to a maximum of 40 mg once daily. The blood pressure-lowering effect appears within 2 weeks of starting treatment and reaches maximum effect in about 8 weeks. If blood pressure is not controlled with monotherapy, it may be used in combination with thiazide diuretics.

Child dose

Safety and efficacy for pediatric use have not been established.

This medication can cause serious harm or death to the fetus and newborn if taken during the second and third trimesters of pregnancy, so it should be discontinued immediately if pregnancy is confirmed. Patients with allergies to this medication or its components should not take it, and it should not be used by pregnant or nursing women, patients on dialysis, those with severe liver dysfunction, or patients with bile duct obstruction. It contains lactose, so patients with lactose intolerance or certain inherited conditions should not take it. Especially in diabetic patients taking aliskiren, this medication should not be used in combination. Patients with low blood volume or sodium may experience hypotensive symptoms, so their conditions should be carefully monitored before taking it, and they should be observed closely afterward. Patients with decreased kidney function or those who have received a kidney transplant should have their kidney function and electrolyte status regularly checked with blood tests. Patients with renal artery stenosis should also be careful as prolonged use of this medication may worsen kidney function. This medication can increase potassium levels in the blood, so patients at risk of hyperkalemia should undergo regular blood tests. Patients with aortic stenosis, mitral stenosis, or obstructive cardiomyopathy should exercise caution when taking this medication. Low blood pressure may cause dizziness, so driving or operating dangerous machinery should be avoided. This medication may have somewhat reduced blood pressure-lowering effects in Black patients. While taking this medication, side effects such as dizziness, headache, palpitations, back pain, hematuria, hyperglycemia, hypertriglyceridemia, influenza-like symptoms, pharyngitis, rhinitis, sinusitis, cough, abdominal pain, indigestion, gastritis, nausea, hypercholesterolemia, hyperlipidemia, hyperuricemia, arthralgia, arthritis, myalgia, hair loss, pruritus, diarrhea, and elevated blood pressure may occur, but most are mild and temporary. Severe side effects may include angioedema, liver function abnormalities, hyperkalemia, acute renal failure, elevated serum creatinine, urticaria, severe allergic reactions, severe swelling, asthma, facial swelling, elevated blood pressure, increased serum creatinine, peripheral edema, and headache (which may include serious neurological symptoms); if any unusual symptoms occur, consult a doctor immediately. If chronic diarrhea and weight loss persist, discontinue the medication and seek specialist care. When combined with other medications, interactions may occur with potassium-sparing diuretics, potassium supplements, lithium preparations, and non-steroidal anti-inflammatory drugs, so it is essential to inform your doctor or pharmacist. Pregnant women should not take this medication, and nursing mothers should discontinue breastfeeding or stop the medication, as side effects may appear in infants. Safety for pediatric use has not been established, so it is advisable not to use it in children. Elderly patients may have higher drug concentrations in their bodies, so dose adjustments and caution are required. In case of overdose, hypotension and palpitations may occur; if symptoms are severe, immediate medical attention is necessary.

Serious side effects

Urticaria, angioedema, anaphylactic reaction, intestinal angioedema, rhabdomyolysis, hyperkalemia, acute renal failure, increased serum creatinine, urticaria, liver function abnormalities (increased liver enzymes and bilirubin), severe allergic reactions, severe swelling, asthma, facial swelling, elevated blood pressure, increased serum creatinine, peripheral edema, headache (which may include serious neurological symptoms)

Mild side effects

• Dizziness
• headache
• palpitations
• back pain
• hematuria
• hyperglycemia
• hypertriglyceridemia
• influenza-like symptoms
• pharyngitis
• rhinitis

This medication should be stored in a tightly closed container to protect it from air and moisture. It is advisable to keep the storage temperature between 1 degree and 25 degrees Celsius at room temperature.

Appearance

White oval film-coated tablet

Package unit

28 tablets (14 tablets/PTP X 2)/carton