Diamicron MR 60 mg (Gliclazide)

Adult dose

Adults: Gliclazide 30~120 mg orally, once daily in the morning, adjusting dose based on blood sugar levels. It is recommended to swallow the tablet whole without crushing or chewing. In case of missed doses, do not increase the next day's dose. The initial recommended dose is 30 mg/day. If blood sugar control is not satisfactory, the dose may be gradually increased to 60, 90, or 120 mg at least every month.

This drug is a sulfonylurea that lowers blood sugar, but it carries a risk of hypoglycemia, so caution is needed. In particular, severe hypoglycemia can lead to coma, so strict adherence to dosages is necessary. This drug should not be administered to patients with diabetic ketoacidosis, diabetic coma, type 1 diabetes, severe liver or kidney function impairment, patients with severe infections or post-operative patients, or those with gastrointestinal disorders. Additionally, it should not be used in patients with known allergic reactions to this drug or similar drugs, pregnant or breastfeeding women, or patients with certain genetic lactose metabolism disorders. Caution should also be exercised in patients who are uncooperative, elderly, suffer from mild to moderate kidney or liver function impairment, certain endocrine disorders, poor nutritional status or irregular eating habits, vigorous exercisers, or excessive drinkers as they are at a higher risk for hypoglycemia. During treatment, watch for symptoms of hypoglycemia such as weakness, headache, confusion, sweating, palpitations, and consume carbohydrates immediately if symptoms occur. Immediate medical care is necessary for severe hypoglycemia, and in some cases, hospitalization may be required. This drug may also cause side effects such as hematological abnormalities, liver dysfunction, gastrointestinal symptoms, skin rashes, temporary visual disturbances, so consult healthcare professionals if these symptoms occur. This drug is used when diet and exercise do not provide sufficient effectiveness, and regular checks of blood sugar and urine sugar should be conducted to monitor effectiveness and side effects. Moreover, this drug can interact with multiple medications, so inform your healthcare professional of any other drugs you are taking. Particularly, it should not be used concurrently with drugs such as miconazole, and alcohol intake should also be avoided. Pregnant or potentially pregnant women and breastfeeding mothers should not use this medication, and safety in children has not been established. Elderly patients are at higher risk for hypoglycemia and should be administered with greater caution and undergo regular testing. In cases of overdose, symptoms of hypoglycemia may occur, so immediate emergency treatment should be sought, as self-treatment can be dangerous. While taking this medication, caution should be exercised regarding hypoglycemic symptoms when driving or operating machinery, and it should be stored out of reach of children.

Serious side effects

Hives, severe swelling (edema), tightness in the chest, difficulty breathing, cold sweat, pallor, severe allergic reactions, severe rashes with fever, blisters, skin peeling, pain in oral/ocular mucosa, severe skin reactions, difficulty or shortness of breath, asthma attacks, respiratory problems accompanied by coughing and fever, skin or eyes turning yellow (jaundice), severe lethargy, liver dysfunction (jaundice), sudden

Mild side effects

• Weakness
• extreme hunger
• tremors
• headache
• paraesthesia
• agitation
• decreased concentration
• aggression
• nausea
• vomiting

This medication should be stored in a tightly closed container to protect it from air and moisture. It is important to maintain storage temperatures between 1 and 30 degrees Celsius.

Appearance

White, oval extended-release tablet with a score line marked “DIA60" on both sides.

Package unit

90 tablets (15 tablets/PTP x 6)