Topstatin 10mg Tablets (Rosuvastatin Calcium)

Adult dose

Start with 5 mg once daily at any time during the day, regardless of meals. If necessary, maintain at 10 mg once daily and adjust according to LDL cholesterol levels and therapeutic goals at intervals of four weeks or more. The maximum dose is 20 mg once daily.

Child dose

Pediatric patients aged 10 to 17 years are administered between 5 mg and 20 mg once daily, adjusted individually based on therapeutic goals. Dose adjustments should be made at intervals of four weeks or more.

This drug should not be used in certain patients. For example, it should not be administered to patients with allergies to any components of this drug, patients with severely impaired liver function, or those with muscle diseases. Moreover, it is advisable for pregnant or nursing women, as well as fertile women not using adequate contraception, to avoid this medication. This drug may affect liver function, so patients with a history of liver disease or those consuming excessive alcohol should undergo multiple liver function tests before administration. Patients with hypothyroidism or kidney disease should also use this drug with caution, and if they experience muscle-related side effects like myalgia or myopathy, they must promptly inform their doctor. Additionally, this drug may interact with other medications, so be sure to inform your physician or pharmacist of any other medications you are taking. Particularly, the risk of muscle damage may increase when used with some antibiotics, antifungals, immunosuppressants, and fibrate medications. If symptoms such as myalgia, weakness, or fever occur during the treatment with this drug, immediately notify medical personnel, and also carefully observe for rare but severe skin reactions or liver damage. Women planning to become pregnant or who are pregnant should not use this drug, and if pregnancy occurs while taking this medication, they should stop taking it immediately and consult a doctor. In cases of overdose, there is no specific antidote, so symptomatic treatment and liver and muscle function testing are necessary. This drug does not appear to significantly affect the ability to drive or operate machinery, but caution is advised due to the potential for dizziness. Finally, as this drug may have higher blood concentrations in Asians, dosage adjustments may be necessary.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, Stevens-Johnson syndrome, drug reaction with eosinophilia and systemic symptoms (DRESS), jaundice, severe muscle weakness, ocular myasthenia, rhabdomyolysis, acute renal failure, oliguria, thrombocytopenia, elevated serum creatinine, severe allergic reactions, severe skin adverse reactions, respiratory problems, liver abnormalities (jaundice), severe neurological symptoms, serious

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• rash and hives
• myalgia
• weakness
• hematuria

This medication may be sensitive to air or moisture, so it must be stored in a tightly closed container. It is recommended to keep it at room temperature between 1 degree and 30 degrees Celsius. This will help maintain the drug's effectiveness over time.

Appearance

Pink, round, film-coated tablets

Package unit

Blister - 28 tablets/box [(14 tablets/blister) x 2], Bottle - 30 tablets/bottle