Medication info
Candetan Plus Tablets

Candetan Plus Tablets

Prescription medicationTablet경구
Ingredient · strength
Candesartan Cilexetil›16mg / 1 tabletHydrochlorothiazide›12.5mg / 1 tablet
Manufacturer / importer
(주)경보제약
Appearance
Light pink rectangular tablet with a bi-convex shape on both sides.
Packaging
30 tablets/bottle, 100 tablets/bottle
Approval status
Active

MFDS item code 200902279 · Notified 2009.03.30 · Insurance code 665001240

Summary

Main use
Improvement of essential hypertension
Who takes it
Adults
Adult dose
The recommended dosage of this medication is 1 tablet once daily, regardless of meal timing. Adults may switch directly to this medication after adjusting the dose of candesartan cilexetil. The antihypertensive effect is typically observed within 4 weeks of starting treatment. No special dosage adjustment is needed for elderly patients. In patients with reduced effective blood volume, and in those with mild to moderate kidney or liver impairment, it is recommended to adjust the dose of candesartan cilexetil.

Ingredients

Manufacturer
(주)경보제약

Efficacy & effects

Improvement of essential hypertension

  • Essential hypertension
View approved original text

Essential hypertension is a condition where blood pressure remains continuously elevated, and individual ingredient treatment may not be sufficient. In such cases, it is important to use a medication that acts with multiple ingredients to more effectively control blood pressure. This can lead to stable management of blood pressure and a reduction in the risk of cardiovascular diseases. Therefore, this medication is used for essential hypertension that is not adequately treated with single medications.

How to take

Adult dose

The recommended dosage of this medication is 1 tablet once daily, regardless of meal timing. Adults may switch directly to this medication after adjusting the dose of candesartan cilexetil. The antihypertensive effect is typically observed within 4 weeks of starting treatment. No special dosage adjustment is needed for elderly patients. In patients with reduced effective blood volume, and in those with mild to moderate kidney or liver impairment, it is recommended to adjust the dose of candesartan cilexetil.

Precautions

This medication can cause serious harm to the fetus and newborn during pregnancy, particularly in the second and third trimesters, so it should be discontinued immediately if pregnancy is confirmed. Do not take this medication if you are allergic to any of its ingredients or to sulfonamide medications. It should also not be administered to patients with acute kidney failure or severe liver disorders, or to patients with certain genetic disorders. Patients with electrolyte imbalances in the blood or specific heart diseases should be particularly cautious when using this medication, and it should be administered carefully according to a doctor’s instructions. As this medication lowers blood pressure, it is advisable not to start taking it in patients with excessively low blood pressure or low blood volume until symptoms improve. During treatment with this medication, mild side effects such as headaches, dizziness, fatigue, and digestive discomfort may occur. If these symptoms persist or worsen, consult a doctor. The hydrochlorothiazide component can affect the body's electrolyte balance, so it is necessary to regularly check electrolyte levels through blood tests. This medication may interact with other blood pressure medications, diuretics, potassium supplements, etc., so if you are taking other medications, be sure to inform your doctor or pharmacist. Women who are pregnant or breastfeeding should not use this medication, and it is recommended to discontinue breastfeeding while taking this medication. Elderly patients should take this medication carefully under the guidance of a doctor, as there is a risk of excessively low blood pressure. Overdose may result in symptoms such as dizziness, hypotension, vomiting, so seek immediate medical attention for appropriate treatment. The safety and efficacy of this medication have not been established in children and adolescents, so it is advisable not to use it in individuals under 18 years of age. Store in a place out of reach of children, and keep it in its original container to maintain quality.

Side effects and when to seek care immediately

Serious side effects

Rash, angioedema, intestinal edema, severe swelling (edema), chest tightness, difficulty breathing, cold sweats, pallor, severe rash with high fever, blisters, skin peeling, pain in the mucous membranes of the mouth/eyes, yellowing of the skin or eyes (jaundice), extreme fatigue, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, significant decrease in urine output, severe swelling of the body and blood.

Mild side effects

Headache, back pain, dizziness, respiratory infections, symptoms similar to a common cold, sinusitis, bronchitis, urinary tract infection, nausea, bruising, tachycardia, fatigue, abdominal pain, pharyngitis, dyslipidemia, nasopharyngitis, cough, weakness, sleep disorders, depression, anxiety, diarrhea, loss of appetite, gastrointestinal irritation, constipation, muscle pain, muscle cramps, hyperglycemia, hyperuricemia, electrolyte imbalance (hyponatremia, hypokalemia, etc.), orthostatic hypotension.

Not everyone experiences these, and they can vary from person to person.

Storage

This medication is sensitive to air and moisture; therefore, it must be stored in a tightly sealed container. It is also important to store it in a cool place below 30 degrees Celsius to maintain its efficacy.

Appearance and packaging

Appearance

Light pink rectangular tablet with a bi-convex shape on both sides.

Package unit

30 tablets/bottle, 100 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.