Medication info

Notobajung 5mg/20mg

Prescription medicationTablet경구Expired
Ingredient · strength
Atorvastatin Calcium›20.72mg / 1 tabletAmlodipine Besylate›6.94mg / 1 tablet
Manufacturer / importer
오스틴제약(주)
Appearance
White oval film-coated tablet
Packaging
30 tablets/bottle
Approval status
Expired

MFDS item code 200809817 · Notified 2008.09.25

This product's status changed to Expired on 2024.10.01. It may no longer be sold, so consult a doctor or pharmacist before taking it.

Summary

Main use
(Hypertension, angina) Reduction of cardiovascular risk and (hypercholesterolemia) improvement in lipid levels
Who takes it
Adults
Adult dose
For Amlodipine (Es Amlodipine), the recommended starting dose is 5 (2.5) mg once daily, which can be increased to a maximum of 10 (5) mg once daily depending on the patient's response. Atorvastatin should be initiated at a recommended dose of 10 mg once daily, with the possibility to start at 20 mg or 40 mg once daily if needed. The dosage should be individualized based on therapeutic goals and can range from 10 mg to 80 mg once daily.

Ingredients

Manufacturer
오스틴제약(주)

Efficacy & effects

(Hypertension, angina) Reduction of cardiovascular risk and (hypercholesterolemia) improvement in lipid levels

  • Hypertension
  • fixed obstruction of coronary arteries
  • vascular spasms of coronary circulation
  • vasoconstriction
  • myocardial ischemia
  • angina
  • heart failure
  • decreased cardiac output
  • myocardial infarction
  • stroke
  • revascularization
  • chronic stable angina
View approved original text

This medication is used for patients who need to take two drugs, Amlodipine (Es Amlodipine) and Atorvastatin, simultaneously. Amlodipine is used for the treatment of hypertension and angina caused by fixed obstruction of coronary arteries or vascular spasms, reducing the risk of hospitalization and revascularization related to angina. Atorvastatin helps reduce the risk of cardiovascular disease and assists in controlling cholesterol levels in patients with hypercholesterolemia and dyslipidemia. It is also effective in reducing the risk of myocardial infarction and stroke in diabetic patients, as well as the risk of hospitalization due to congestive heart failure. In summary, this medication is used for the prevention and treatment of cardiovascular disease and the improvement of lipid metabolism.

How to take

Adult dose

For Amlodipine (Es Amlodipine), the recommended starting dose is 5 (2.5) mg once daily, which can be increased to a maximum of 10 (5) mg once daily depending on the patient's response. Atorvastatin should be initiated at a recommended dose of 10 mg once daily, with the possibility to start at 20 mg or 40 mg once daily if needed. The dosage should be individualized based on therapeutic goals and can range from 10 mg to 80 mg once daily.

Precautions

This medication should not be administered to certain patients. First, patients who have had allergic reactions to this medication or similar class drugs should not use it. Additionally, patients with severely impaired liver function or active liver disease, or those with unexplained extremely high liver enzyme levels should not take this medication. Pregnant women or women of childbearing potential should not take this medication due to risks to the fetus, and nursing mothers should also avoid using it. Patients with muscle diseases, severe aortic stenosis, shock, within one month after myocardial infarction, and those with unstable angina should also refrain from taking this medication. Patients currently taking Glecaprevir and Pibrentasvir should not use this medication. This medication should be used cautiously in patients with severely impaired kidney function, elderly patients, alcoholics, and patients with a history of liver disease. For patients at risk of muscle damage, muscle enzyme levels should be checked before administration, and careful monitoring is required. Patients with acute heart failure or hypertensive crises, and those with moderate liver dysfunction should also be cautious when taking this medication. Generally, this medication is well tolerated; however, some patients may experience symptoms such as flushing, fatigue, edema, dizziness, headache, indigestion, muscle pain, rash, and liver dysfunction; if abnormal symptoms occur, immediate consultation with a doctor is necessary. This medication may interact with other drugs, so it is crucial to inform healthcare providers of any other medications being taken. Special attention is needed when used in combination with drugs metabolized by the liver or those that increase the risk of muscle damage. Pregnant or nursing women should not use this medication, and women of childbearing potential should use adequate contraception while taking it. Safety and efficacy in children and the elderly have not been sufficiently established, so caution should be exercised according to the physician's judgment. In case of overdose, hypotension and heart problems may occur, so immediate medical attention is necessary. This medication should be kept out of reach of children, and it is safer not to transfer it to another container.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), difficulty breathing, severe allergic reactions, toxic epidermal necrolysis, severe skin reactions, jaundice, liver abnormalities (jaundice), sudden and severe headache, seizures, confusion, visual disturbances, paralysis, serious neurological symptoms, markedly reduced urine output, severe swelling throughout the body along with hypertension, severe edema or urinary disturbances, asthma attacks, respiratory issues accompanied by cough and fever,

Mild side effects

  • Flushing
  • fatigue
  • edema
  • palpitations
  • dizziness
  • headache
  • drowsiness
  • abdominal pain
  • nausea
  • weakness
Show 25 more
  • lethargy
  • pain
  • weight gain/loss
  • hypotension
  • vasculitis
  • muscle tension
  • sensory loss/altered sensation
  • peripheral neuropathy
  • fainting
  • altered taste
  • tremor
  • extrapyramidal disorder
  • erectile dysfunction
  • gynecomastia
  • changes in bowel habits
  • dry mouth
  • indigestion
  • gingival hypertrophy
  • gum enlargement
  • pancreatitis
  • vomiting
  • hyperglycemia
  • joint pain
  • low back pain
  • muscle cramps

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to prevent air or moisture from entering, and should be kept in a cool place between 15 to 30 degrees Celsius. Proper storage will help maintain the effectiveness of the medication for a longer period.

Appearance and packaging

Appearance

White oval film-coated tablet

Package unit

30 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.