DuoTan Tablet 160/12.5mg

Adult dose

The recommended adult dosage is 1 tablet once daily of Valsartan 80 mg/Hydrochlorothiazide 12.5 mg, taken with a small amount of water regardless of meals. Valsartan 160 mg/Hydrochlorothiazide 12.5 mg can be applied when prescribed for blood pressure reduction. The maximum effect of blood pressure reduction is observed after 2 to 4 weeks. In patients with renal impairment, mild to moderate renal impairment (creatinine clearance 30 mL/

This medicine can cause serious harm to the fetus if taken during pregnancy, particularly in the second and third trimesters, so it should be discontinued immediately upon confirmation of pregnancy. Patients with allergies to any components of this medication or to sulfonamide drugs, as well as those with severe liver or kidney impairment, should not take this medication. If there are electrolyte imbalances such as hypokalemia, hyponatremia, or hypercalcemia, symptoms may worsen with the use of this medication, so caution is needed. Since this medication lowers blood pressure, dizziness or symptoms of hypotension may occur, particularly in the first few days of use, so vigilance is necessary. Do not take potassium supplements or potassium-containing medications without consulting a doctor, and regularly check serum potassium levels. This medication may increase sensitivity of the skin to sunlight, so take care to use sunscreen while taking this, and inform a doctor immediately if any skin lesions occur. Caution should be exercised when driving or operating machinery, as dizziness or drowsiness may occur. There may be interactions with other medications, so particularly when combined with lithium preparations, NSAIDs, or potassium-sparing diuretics, follow a doctor's instructions. Patients with reduced kidney function or the elderly should periodically check kidney function and electrolyte status while taking this medication. This medication is not recommended for breastfeeding women, and safety and effectiveness in children have not been sufficiently established. In case of overdose, symptoms may include hypotension, electrolyte abnormalities, and muscle cramps, so immediate medical attention is required. This medication should be stored in a sealed container away from moisture and direct sunlight, out of reach of children.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, peeling skin, pain in oral/eye mucosa, shortness of breath or difficulty breathing, asthma attack, respiratory abnormalities accompanied by cough and fever, yellowing of skin or eyes (jaundice), severe lethargy, sudden and severe headache, thunderclap headache, seizures, altered consciousness, visual disturbance, paralysis, urination

Mild side effects

• Headache
• dizziness
• nasopharyngitis
• fatigue
• back pain
• cough
• upper respiratory infection
• diarrhea
• joint pain
• abdominal pain

This medication is sensitive to air and moisture, so it should be stored in a sealed container. It is best to keep the storage temperature below 30 degrees Celsius to prolong the effectiveness of the medication.

Appearance

Dark red oval film-coated tablet

Package unit

28 tablets/PTP [14 tablets/PTP packaging x 2]