Cositane Plus Tablet

Adult dose

The usual dosage of this medication is one tablet of Losartan Potassium 50 mg/Hydrochlorothiazide 12.5 mg once daily. A dosage exceeding Losartan Potassium 100 mg/Hydrochlorothiazide 25 mg per day is not advisable. - Patients whose blood pressure is not controlled by monotherapy with Losartan or Hydrochlorothiazide should start treatment with one tablet of Losartan Potassium 50 mg/Hydrochlorothiazide 12.5 mg once daily.

Child dose

There is no experience in using this drug in children and adolescents, therefore the combination of losartan and hydrochlorothiazide is not administered to children and adolescents.

This medication can cause serious harm to the fetus and newborn, especially during pregnancy, so it should be discontinued immediately if pregnancy is confirmed. This medication should not be used in individuals with specific allergic reactions or in patients with severely impaired kidney or liver function. Patients with hypotension or electrolyte imbalances should use this medication with caution, as blood pressure may drop too low, and their condition should be closely monitored. This medication may increase the risk of skin cancer, so it is advisable to reduce sun exposure and regularly check skin conditions. Dizziness or drowsiness may occur during treatment, so caution is advised when driving or operating machinery. Regular blood tests to check electrolyte levels and kidney function should be conducted, and any abnormalities must be discussed with healthcare professionals. Due to potential interactions with other medications, it is essential to inform your healthcare provider of any other medications being taken, especially potassium supplements or drugs containing potassium, which should not be used together. This medication may also affect breastfeeding infants, so it is necessary to either discontinue breastfeeding or consult with a physician. Use in children or adolescents is not recommended as safety has not been established.

Serious side effects

Hives, angioedema (swelling of lips and eyelids and facial rash), angioedema (swelling of the larynx/epiglottis causing airway obstruction, swelling of the face/lips/pharynx/tongue), vasculitis (including Henoch-Schönlein purpura), anaphylaxis, severe swelling (edema), thrombocytopenia, severe rash with high fever, blistering, skin peeling, pain in oral/eye mucosa, skin-mucosal syndrome (Stevens-Johnson syndrome, toxic epidermal necrolysis)

Mild side effects

• Abdominal pain
• swelling
• palpitations
• back pain
• dizziness
• cough
• sinusitis
• upper respiratory infection
• weakness/fatigue
• diarrhea

This medication is sensitive to light and should be stored in a container that blocks light. Additionally, it should be stored at room temperature between 1 to 30 degrees Celsius and not in excessively hot or cold places.

Appearance

Yellow oval film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle