Impactasol Injection

Adult dosage

The total amino acid dosage should be administered by intravenous drip at a maximum dose of 1 to 1.5 g per kg of body weight per day. An infusion rate of approximately 10 g of total amino acids over 60 minutes is preferred, and the principle is to administer 30 to 40 drops per minute.

Children's dosage

In children, the dosage and infusion rate should be adjusted accordingly.

This medication should only be used according to a doctor's instructions. It should not be administered to patients with hepatic coma or those at risk of hepatic coma, patients with severe renal impairment, and patients with hyperammonemia or certain metabolic disorders. It is also safe not to use in patients with heart failure, pulmonary edema, oliguria, anuria, hypernatremia, or hyperkalemia. Additionally, it should not be used in patients with atrioventricular block, myasthenia gravis, hereditary amino acid metabolism disorders, or those who have allergies to the amino acids contained in this medication. Caution should be taken when administering to patients with severe acidosis, congestive heart failure, edema due to sodium retention, hepatic or renal impairment. This medication contains sodium bisulfite, which may cause allergic reactions or asthma attacks in some patients, so caution is required. During administration, various side effects such as rash, nausea, vomiting, chest discomfort, palpitations, and increased blood pressure may occur, and if symptoms arise, medical personnel should be consulted immediately. Rapid infusion of large amounts may lead to acidosis, and rarely, serious symptoms such as chills, fever, headache, and dyspnea may occur. Patients with liver or kidney failure may have changes in blood test values, so periodic testing is necessary. Electrolyte balance should be carefully monitored during administration, especially when used with electrolyte solutions. Diabetic patients should frequently check their blood sugar levels, and when administering amino acid solutions alone, ketone bodies may accumulate, so it is advisable to administer with carbohydrates. The safety of this medication in pregnant women has not been established, and it should only be administered when the therapeutic effect outweighs the risk. Infants and young children may have immature liver function, so doses should be reduced and blood ammonia levels should be tested frequently. Elderly patients may have decreased bodily functions, so the rate of administration should be slow and the dosage adjusted. Infusion should be done slowly through the vein, as rapid infusion may cause chills or vomiting. The solution should be adjusted to body temperature for use and must be prepared and managed in a sterile condition to reduce the risk of infection. Before use, check that the solution is clear and without abnormalities, and do not use solutions that are discolored or leaked. During storage, it should be kept in a sealed container to prevent exposure to air, and it is important to maintain a storage temperature between 1 degree and 30 degrees Celsius. Storing it this way ensures that the medication's effectiveness is safely maintained.

Serious side effects

• Hives
• dyspnea
• asthma attack
• chest tightness
• elevated blood pressure
• coma

Mild side effects

• Rash
• nausea
• vomiting
• chest discomfort
• palpitations
• tachycardia
• increased blood pressure
• metabolic acidosis
• hypophosphatemia
• alkalosis

This medication should be stored in a sealed container to prevent exposure to air, and it is important to maintain a storage temperature between 1 degree and 30 degrees Celsius. Storing it this way ensures that the medication's effectiveness is safely maintained.

Appearance

A colorless to light yellow transparent solution in a colorless transparent glass vial with a rubber stopper for infusion

Package unit

250mL/vial x 1, 250mL/vial x 10