Piglito Tablet 15 mg (Pioglitazone Hydrochloride)

Adult dose

This drug is orally administered once a day irrespective of meals. As monotherapy, it can be started at a dose of 15 mg once daily, and if insufficiently effective, it may be increased to a dose of up to 30 mg once daily. In combination therapy, the initial dose is 15 mg once daily, and it should not exceed 30 mg once daily.

Child dose

There is no experience in children under 18 years old, hence administration is not recommended.

This drug is used for the treatment of type 2 diabetes and it is effective in lowering blood glucose only when insulin is present. This drug can exacerbate or newly induce heart failure, hence it should not be used in patients with heart failure or a history of heart failure. If symptoms of heart failure such as sudden weight gain, shortness of breath, or swelling occur, immediate medical attention should be sought, and the drug's administration should be discontinued or the dosage adjusted as necessary. This drug can lead to fluid retention and cause swelling, so caution is required in patients with edema or heart disease. It should not be administrated to patients with active bladder cancer or a history of bladder cancer, and any symptoms of hematuria or urination disorders during treatment should be reported to a physician immediately. Patients with impaired liver function, severe renal impairment, diabetic ketoacidosis, or type 1 diabetes should not use this drug. Women who are pregnant or may become pregnant are advised against using this drug, and premenopausal women may experience enhanced ovulation with an increased risk of pregnancy, thus appropriate contraception should be utilized. The risk of hypoglycemia may increase when this drug is used in combination with other hypoglycemic agents, therefore dosage adjustments of co-administered medications may be necessary. During the course of taking this medication, regular blood glucose and liver function tests should be performed, and immediate consultation with a doctor should occur if there are symptoms such as weight gain, edema, or shortness of breath. Elderly patients or those with impaired renal function also need careful consideration when using this drug, and appropriate treatment should be provided according to symptoms in case of overdose. This drug should be taken orally once a day irrespective of meals, and care should be taken not to double the dose the next day if a dose is missed. There may be interactions with other medications taken concurrently, so it is essential to inform the physician or pharmacist about any other medications being used.

Serious side effects

Congestive heart failure, symptoms and signs of heart failure (including excessive and rapid weight change, dyspnea, and edema), severe edema, bladder cancer, liver abnormalities (jaundice, liver failure, worsening of liver disease), hives, stroke, myocardial infarction, severe neurological symptoms, dyspnea, numbness, hives, edema, jaundice, severe allergic reactions, increased risk of pregnancy due to ovulation induction in premenopausal women, hospitalization cases due to hypoglycemia, severe heart failure

Mild side effects

• Upper respiratory tract infection
• headache
• sinusitis
• myalgia
• pharyngitis
• abdominal bloating
• weight gain
• urinary tract infection
• hypoglycemia
• lumbago

This drug should be stored in a special container that protects it from light and air, and it should be kept in a dry environment. Additionally, it is advisable to store the drug at a temperature between 15 degrees and 30 degrees Celsius.

Appearance

White or nearly white round tablets

Package unit

30 tablets/bottle, 100 tablets/bottle