Piofine Tablets 15mg (Pioglitazone Hydrochloride)

Adult dose

This medication is taken orally once daily, regardless of meals. Starting as monotherapy, it is administered at a dose of 15 mg once daily, and if the effect is insufficient, the dose may be increased to 30 mg once daily. In cases of combination with sulfonylureas, metformin, or insulin, the initial dose is 15 mg once daily, and the maximum recommended dose does not exceed 30 mg once daily.

Child dose

There is no experience with use in pediatric patients under 18 years of age; therefore, administration is not recommended.

This medication is used for the treatment of type 2 diabetes and works to improve insulin resistance. This medication may burden the heart in some patients and should not be used in patients with heart failure or a history of heart failure. During treatment, weight gain and edema may occur, and if these symptoms appear, consult a physician. Moreover, this medication should not be administered to patients with a history of bladder cancer or those with active bladder cancer. Patients with impaired liver function or severe renal impairment should use this medication with caution. Women who are pregnant or may become pregnant must consult a physician before taking this medication, and it is advisable for premenopausal women to take appropriate measures to prevent pregnancy. When used in combination with other hypoglycemic agents, the risk of hypoglycemia may increase, so it is essential to carefully monitor the associated medications and symptoms. During treatment, regular blood sugar and liver function tests should be conducted, and any sudden weight gain, shortness of breath, or edema should be reported immediately to healthcare professionals. In case of overdose, there may not be any specific symptoms; however, appropriate treatment must be obtained according to medical advice. This medication should not be used in children or adolescents under 18 years of age, as safety and efficacy have not been established. It should be administered to elderly patients with caution, especially those over 75 years old.

Serious side effects

Congestive heart failure, symptoms and signs of heart failure (dyspnea, edema, etc.), severe edema, severe allergic reactions (such as hives), liver abnormalities (jaundice, fatal and non-fatal liver failure), severe neurological symptoms (headaches, seizures, confusion of consciousness, etc.), lung diseases and respiratory problems (difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough + fever), myocardial infarction, stroke, skin reactions (severe rashes with high fever, blisters, skin

Mild side effects

• Upper respiratory infection
• headache
• sinusitis
• myalgia
• pharyngitis
• abdominal distension
• weight gain
• urinary tract infection
• diarrhea
• back pain

This medication should be stored in a tightly sealed container to protect it from air and moisture. Additionally, it is best to keep the medication at room temperature between 1 to 30 degrees Celsius, away from extreme heat or cold.

Appearance

White to grayish-white, convex cylindrical tablets

Package unit

30 tablets/bottle, 100 tablets/bottle