Lipyone Tablet 10 mg (Atorvastatin Calcium Trihydrate)

Adult dose

For the treatment of hyperlipidemia, the recommended initial dose is 10 mg of atorvastatin once daily, and if a greater reduction in LDL cholesterol is needed, it can be started at 20 mg or 40 mg once daily. This medication is administered at a dose range of 10 to 80 mg once daily, with the initial and maintenance doses individualized based on patient characteristics. After starting treatment and adjusting the dose, lipid levels should be analyzed within 2 to 4 weeks for further adjustments.

Child dose

The recommended initial dose for pediatric patients with heterozygous familial hypercholesterolemia (ages 10 to 17) is 10 mg once daily, with a maximum recommended dose of 20 mg once daily. The dosing should be appropriately adjusted according to the treatment goals for each patient.

This medication may cause muscle-related symptoms; therefore, if severe muscle pain, weakness, or cramps occur, discontinue use immediately and consult a physician. Treatment should be stopped if muscle enzyme levels are significantly elevated or if muscle disease is suspected. Patients with active liver disease or severely impaired liver function should not take this medication. Women who are pregnant, may become pregnant, or are breastfeeding, as well as children under 10 years of age, should not use this medication. Patients with a history of alcohol abuse or liver disease must exercise caution when taking this medication and should have regular liver function tests. Since this medication may affect liver function, any symptoms such as nausea, vomiting, or fatigue should be reported to a doctor immediately. Regular monitoring of liver function and muscle status is important while on this medication. Caution is required when taking this drug with other medications, especially certain antibiotics, antifungals, HIV treatments, and other lipid-lowering agents. Taking grapefruit juice with this medication may increase its blood concentration, so grapefruit juice should be avoided. This medication contains lactose, so patients with lactose intolerance should not take it. Adequate contraceptive methods should be used while on this medication, and use should be discontinued immediately if pregnancy is confirmed. Elderly patients and those with impaired renal function are at greater risk for muscle disease and should be monitored closely during use. There is no specific antidote for overdose; thus, treatment should be symptomatic, along with monitoring of liver function and muscle enzyme levels. This medication should be stored out of reach of children and kept in its original container.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe allergic reactions, severe rash with fever, blisters, skin peeling, mouth/eye mucosal pain, severe skin adverse reactions, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by coughing and fever, yellowing of skin or eyes (jaundice), significant systemic lethargy, liver abnormalities (jaundice), sudden and severe symptoms.

Mild side effects

• Weakness
• fatigue
• chest pain
• peripheral edema
• tiredness
• fever
• nasopharyngitis
• hyperglycemia
• hypoglycemia
• weight gain

This medication may be sensitive to air or moisture, so it should be stored in a tightly sealed container. It is recommended to keep it at a room temperature that is not too hot or too cold.

Appearance

White oval film-coated tablets

Package unit

Domestic: 30 tablets/bottle, 100 tablets/bottle Export: 30 tablets (10 tablets/PTP x 3)