Rabesto Tablet 20 mg (Rabeprazole Sodium)

Adult dose

For gastric ulcer and duodenal ulcer: The adult dose is 10 mg of rabeprazole sodium taken orally once daily, which may be increased to 20 mg once daily as needed, up to 8 weeks for gastric ulcers and up to 6 weeks for duodenal ulcers. For erosive or ulcerative gastroesophageal reflux disease: Administer 10 mg or 20 mg once daily for 4 to 8 weeks. If proton pump inhibitors (PPIs) are not effective after 8 weeks of treatment, additional treatment with 10 mg or 20 mg twice daily may be necessary, but 20 mg twice daily is only for patients with confirmed severe mucosal damage. For relief of symptoms of gastroesophageal reflux disease: Administer 10 mg once daily. If symptoms do not improve after 4 weeks, further evaluation is necessary. Once symptoms resolve, an on-demand therapy of 10 mg once daily can be employed to manage any recurrent symptoms. For long-term maintenance therapy of gastroesophageal reflux disease: Depending on the patient, 10 mg or 20 mg may be given orally once daily. For eradication of Helicobacter pylori: Patients infected with Helicobacter pylori should be treated with eradication therapy. It is recommended to administer 20 mg of this medicine along with 500 mg of clarithromycin and 1 g of amoxicillin, twice daily for 7 days. For Zollinger-Ellison syndrome: The recommended initial dose for adults is 60 mg once daily, with adjustments made based on individual patient needs up to a maximum of 120 mg daily. Doses up to 100 mg may be given once daily, while doses of 120 mg should be divided into two doses of 60 mg twice daily. Patients with Zollinger-Ellison syndrome may have been treated with this medicine for up to a year. ● For patients with liver impairment: Adverse reactions of hepatic encephalopathy have been reported in cirrhosis patients. Therefore, caution should be exercised when administering. ● In children: Safety in pediatric patients has not been established. ● In elderly patients: Caution should be exercised because liver function is often impaired.

This medicine should not be used in patients with known allergies or hypersensitivity to certain ingredients. In particular, patients allergic to penicillin or macrolide antibiotics, those taking certain heart-related medications, and pregnant or breastfeeding women should avoid taking this product for safety reasons. Patients with impaired liver function or elderly individuals, as well as those with a history of drug allergies, should use this medicine with caution. This medicine may cause allergic reactions such as itching or rash, and if such symptoms occur, it should be discontinued immediately. Regular blood tests and liver function tests should be undertaken, and any unusual signs should be reported promptly, as side effects may occur in various organs including cardiac, gastrointestinal, nervous, respiratory, and skin systems. Long-term use of this medicine may increase the risk of bone fractures and decrease magnesium levels in the blood; thus, regular monitoring is advisable. Additionally, as it suppresses gastric acid secretion, there may be a slightly increased risk of bacterial infections in the stomach, so if diarrhea persists, consult a healthcare professional. Caution should be exercised while driving or operating machinery due to potential drowsiness or dizziness. There may be interactions with other medications, so inform healthcare providers about any other medications being taken, especially when taking antibiotics, antiviral agents, or anticoagulants. Pregnant or breastfeeding women should avoid this medicine, and its use in children is not recommended due to lack of established safety. Tablets should not be chewed or crushed, and should be swallowed whole. Keep in a sealed container to avoid exposure to air and store at a temperature between 1°C and 30°C. In case of overdose, there is no specific antidote, so appropriate treatment should be administered based on symptoms.

Serious side effects

Hives, severe swelling, chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanying cough + fever, yellowing of the skin or eyes, extreme lethargy, sudden and severe headache, thunderclap headache, seizures, confusion of consciousness, visual disturbances, paralysis, markedly reduced urine output

Mild side effects

• Rash
• itching
• red blood cell decrease
• white blood cell decrease
• white blood cell increase
• eosinophil increase
• neutrophil increase
• lymphocyte decrease
• anemia
• purpura

This medicine should be stored in a sealed container to prevent exposure to air, preferably at a temperature between 1°C and 30°C. Proper storage helps maintain the effectiveness of the medication for a longer period.

Appearance

Light yellow round enteric-coated tablet

Package unit

28 tablets (14 tablets per pack x 2)