Labetra Tablet 10 mg (Rabeprazole Sodium)

Adult dose

For gastric ulcers and duodenal ulcers: Administer 10 mg orally once a day; may increase to 20 mg once daily based on symptoms. Typically, for gastric ulcers, it is used for up to 8 weeks; for duodenal ulcers, it is used for up to 6 weeks. For erosive or ulcerative gastroesophageal reflux disease: Administer 10mg or 20mg once a day for 4-8 weeks. If untreated, an additional 8 weeks of 10mg or 20mg may be administered twice a day. For those with unresolved symptoms, 10mg or 20mg can be continued for an additional 8 weeks. For symptom relief of gastroesophageal reflux disease: Administer 10mg once daily; if symptoms are not controlled after 4 weeks, further evaluation is necessary. Once symptoms resolve, on-demand therapy with 10mg once daily can be used to manage future symptoms. For long-term maintenance therapy of gastroesophageal reflux disease: Administer 10mg or 20mg orally once daily depending on the patient. For Helicobacter pylori eradication: Patients infected with Helicobacter pylori should undergo eradication therapy. It is recommended to administer 20 mg of this drug combined with clarithromycin 500 mg and amoxicillin 1 g twice a day for 7 days. For Zollinger-Ellison syndrome: The recommended initial dose for adults is 60 mg once daily. The dose can be adjusted up to 120 mg based on individual patient needs. Doses of 100 mg can be given once daily, while 120 mg should be divided into 60 mg doses twice daily. Patients with Zollinger-Ellison syndrome have experienced treatment with this drug for up to one year. In patients with liver impairment, adverse reactions of hepatic encephalopathy have been reported, hence cautious administration is required. In children, safety has not been established. In older adults, caution should be exercised due to frequent liver function impairment.

Child dose

Safety has not been established for pediatric use.

This medication should not be used in patients with allergies or hypersensitivity to specific components or benzimidazoles. Additionally, caution is required for individuals sensitive to penicillin and macrolide antibiotics if using this medication. It is safe for women who are pregnant or breastfeeding to avoid using this medication. Patients with liver dysfunction, elderly individuals, and those with a history of drug allergies should use this drug with caution. This medication can cause allergic reactions such as skin rash, hives, and itching, so it should be discontinued immediately if these symptoms occur. Regular blood tests and liver function tests are important to detect any abnormal signs early. Side effects can occur in various areas, including the heart, gastrointestinal tract, nervous system, respiratory system, and skin, so patients should consult a doctor if symptoms appear. Prolonged use of this medication may increase the risk of osteoporosis and fractures, so caution is necessary during long-term use. It may also lower blood magnesium levels with prolonged use, requiring regular monitoring and potential supplementation. This drug inhibits gastric acid secretion and may increase the risk of certain bacterial infections, so patients should inform their healthcare provider if diarrhea persists. Caution is also advised while driving or operating machinery, as drowsiness may occur. There may be drug interactions, so it is essential to inform your doctor about any other medications being taken, especially when used in conjunction with antibiotics or antivirals. This drug should not be chewed or crushed and must be swallowed whole at once. Keep it out of reach of children, and it is recommended not to transfer it to other containers. Women who are pregnant or breastfeeding should not use this medication, and elderly patients should be cautious due to potential side effects owing to decreased liver function. Safety in children has not been sufficiently established, warranting careful use. There is no specific antidote for overdose; symptomatic treatment should be administered based on the symptoms.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash accompanied by high fever, blisters, peeling skin, pain in mouth/eye mucosa, shortness of breath or difficulty breathing, asthma attack, respiratory abnormalities with cough + fever, yellowing of the skin or eyes (jaundice), severe lethargy, sudden and very severe headache, thunderclap headache, seizures, confusion, vision changes, paralysis, urination

Mild side effects

Occasionally rash, itching, hives, blood abnormalities (anemia, leukopenia, etc.), hypertension, myocardial infarction, abnormal electrocardiogram, migraine, syncope, angina, heart block, palpitations, tachycardia, bradycardia, pulmonary embolism, thrombophlebitis, vasodilation, ventricular tachycardia, diarrhea, constipation, abdominal pain, abdominal bloating, dyspepsia, belching, nausea, rectal bleeding, blood in stool, anorexia, cholelithiasis, oral ulcers, dysphagia, gingivitis, cholecystitis

This medication should be stored in a tightly sealed container to protect it from air and moisture, and the storage temperature should be maintained between 1 to 30 degrees Celsius at room temperature. By storing it this way, the effectiveness and safety of the drug can be maintained for a longer period.

Appearance

Light yellow round enteric-coated tablet

Package unit

28 tablets (14 tablets/PTP packaging x 2) (for export), 28 tablets (14 tablets/AluAlu packaging x 2)