Cozartan Plus Tablets

Adult dose

The usual dosage for adults is 1 tablet containing 50 mg of losartan potassium and 12.5 mg of hydrochlorothiazide once daily. A dosage exceeding 100 mg of losartan potassium and 25 mg of hydrochlorothiazide in a day is not desirable. Start with a dose of 1 tablet containing 50 mg of losartan potassium and 12.5 mg of hydrochlorothiazide once daily, and if blood pressure is not controlled after 3 weeks, the maximum dose may increase to 100 mg of losartan potassium and 25 mg of hydrochlorothiazide.

Child dose

There is no experience in using this medication in children and adolescents (under 18 years old), so it should not be administered.

This medication can cause serious harm to the fetus when taken during pregnancy, especially in the second and third trimesters, so it must be discontinued immediately upon confirmation of pregnancy. This drug should not be prescribed to patients with certain conditions or those who are allergic to the medication, particularly patients with severely impaired kidney function or significant liver dysfunction. During the use of this medication, blood pressure may drop too low, so it is essential to consult a physician immediately if symptoms of hypotension or dizziness occur. As electrolyte imbalances may occur, it is important to regularly check sodium, potassium, and other levels through blood tests. This drug can interact with other medications, so special caution should be taken to avoid using it alongside potassium supplements or medications containing potassium. Due to the hydrochlorothiazide component, skin sensitivity to sunlight may increase; therefore, it is advised to avoid prolonged sun exposure and to pay attention to UV protection. Adverse effects may occur more frequently in older adults, so they should take this medication with extra caution. If symptoms such as cough, rash, or swelling occur during use, it is critical to inform healthcare professionals and seek advice immediately. Care is needed when driving or operating machinery as dizziness or drowsiness may occur. This medication has limited use experience in children and adolescents; therefore, it is best not to administer it to them.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe rash with high fever, blisters, skin peeling, pain in mucous membranes of mouth/eyes, breathlessness or difficulty breathing, asthma attack, respiratory abnormalities accompanying cough and fever, jaundice (yellowing of skin or eyes), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, altered consciousness, visual disturbances, paralysis, urination abnormalities

Mild side effects

• Abdominal pain
• swelling
• palpitations
• back pain
• dizziness
• cough
• sinusitis
• upper respiratory infections
• lethargy/fatigue
• diarrhea

This medication should be stored in a container that blocks light and air, and it is safe to keep it at room temperature between 1°C to 30°C. Storing it this way will help maintain the drug’s efficacy for an extended period.

Appearance

Yellow oval film-coated tablets

Package unit

30 tablets/bottle, 200 tablets/bottle