Medication info
Pendiraz Tablets (Phendimetrazine Tartrate)

Pendiraz Tablets (Phendimetrazine Tartrate)

Prescription medicationTablet경구
Ingredient · strength
Phendimetrazine Tartrate›35mg / 1 tablet
Manufacturer / importer
(주)셀릭스
Appearance
White round tablet
Packaging
30 tablets/bottle, 300 tablets/bottle
Approval status
Active

MFDS item code 200604148 · Approved 2006.04.10

Summary

Main use
Weight loss adjunct therapy for patients with obesity (including risk factors such as hypertension and diabetes)
Who takes it
Adults
Adult dose
Adults: This medication as phendimetrazine tartrate is orally administered as 35 mg once 2 - 3 times a day, one hour before meals. The dose should use the minimum effective amount but should be adjusted individually. For some patients, a dose of 17.5 mg once daily may be appropriate. The dose should not exceed 70 mg three times daily. It is administered for a short duration (within 4 weeks).

Ingredients

Manufacturer
(주)셀릭스

Efficacy & effects

Weight loss adjunct therapy for patients with obesity (including risk factors such as hypertension and diabetes)

  • Obesity
  • hypertension
  • diabetes
  • hyperlipidemia
View approved original text

This medication is used for short-term weight loss assistance in initial obesity patients who find it difficult to lose weight through appropriate dietary or exercise therapy, specifically those with a body mass index (BMI) of 30 or above, or those with risk factors such as hypertension, diabetes, or hyperlipidemia with a BMI of 27 or above. It plays a role in supporting the treatment of exogenous obesity based on calorie restriction, and should be used alone without combining with other appetite suppressants. This medication effectively aids in weight loss therapy and helps improve health conditions.

How to take

Adult dose

Adults: This medication as phendimetrazine tartrate is orally administered as 35 mg once 2 - 3 times a day, one hour before meals. The dose should use the minimum effective amount but should be adjusted individually. For some patients, a dose of 17.5 mg once daily may be appropriate. The dose should not exceed 70 mg three times daily. It is administered for a short duration (within 4 weeks).

Precautions

This medication must not be used in conjunction with other appetite suppressants as it may lead to serious heart conditions. This medication should only be used alone for a short period in the treatment of exogenous obesity, and combining it with other weight loss drugs is not recommended due to lack of safety and effectiveness confirmation. Long-term use of this medication may significantly increase the risk of serious pulmonary vascular disease called pulmonary hypertension, so caution is needed. If symptoms such as shortness of breath during exercise, chest pain, fainting, or leg swelling occur, discontinue the medication immediately and seek medical attention. Caution should be taken to evaluate cardiac status before administration due to potential risks related to valvular heart disease, and it is not recommended for patients with heart murmurs or valvular disorders. Patients with certain conditions, such as hypertension, hyperthyroidism, glaucoma, psychological anxiety, or a history of substance abuse should not take this medication. In addition, children under 16 years old, pregnant women, or women who may become pregnant should not take this medication. This medication affects the central nervous system, so caution is needed when driving or operating machinery. Diabetic patients may need to adjust their insulin dosages. In case of overdose, severe symptoms such as anxiety, coma, seizures, heart irregularities, and vomiting may occur, so it is essential to adhere to the prescribed dosage. Safety has not been established for pregnant or breastfeeding women, and it should be avoided due to the risk of harm to the fetus or infant. This medication is classified as a controlled substance with a risk of abuse, and abrupt discontinuation after prolonged high-dose use may result in severe fatigue and depression. Therefore, this medication should be taken cautiously and under strict medical supervision, and consulting with a healthcare professional should be done immediately if any abnormal symptoms occur.

Side effects and when to seek care immediately

Serious side effects

Rash

Mild side effects

  • Palpitations
  • tachycardia
  • increased blood pressure
  • overstimulation
  • anxiety
  • dizziness
  • insomnia
  • tremors
  • euphoric sensations
  • headache
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  • mental disorders
  • excitement
  • flushing
  • sweating
  • blurred vision
  • dry mouth
  • discomfort
  • diarrhea
  • constipation
  • nausea
  • stomach pain
  • changes in sexual desire
  • frequent urination
  • dysuria
  • erectile dysfunction

Not everyone experiences these, and they can vary from person to person.

Storage

This medication may be sensitive to air and moisture and should be stored in a tightly sealed container. It is important to maintain a storage temperature between 1°C and 30°C to effectively preserve the medication's efficacy and safety.

Appearance and packaging

Appearance

White round tablet

Package unit

30 tablets/bottle, 300 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.