Encaine Cream

Adult dosage

1. Skin: After applying this drug, cover with a sealing tape. The seal on the application area should be maintained for 1-3 hours, and the effect lasts at least 1 hour after removing the tape. 1) When inserting a syringe needle (e.g. venipuncture, blood collection), apply about 2g of this drug for at least 1 hour, up to a maximum of 5 hours. 2) For superficial surgical minor surgeries (e.g. excision of a sebaceous cyst), apply 1.5-2g/10cm2 for 1 hour.

Children's dosage

Infants aged 3 months to 12 months: total amount 2g, applied area not to exceed 16cm2.

This drug is used as a local anesthetic but carries the risk of methemoglobinemia, a blood disorder. Extra caution is necessary for patients with glucose-6-phosphate dehydrogenase deficiency, congenital methemoglobinemia, those with heart or lung damage, infants under 6 months, and when used in conjunction with oxidizing agents. Symptoms may include bluish skin or abnormal changes in blood color, and if these occur, use should be immediately discontinued and medical attention sought. This drug should not be used for patients with hypersensitivity or wounds, mucous membranes, atopic dermatitis, infants under 3 months, and premature infants. Patients with anemia, liver disease, elderly patients, and those who are frail should use with caution, as skin reactions may occur. Common local reactions may include temporary symptoms such as pallor, redness, swelling, mild initial burning sensation, itching, tingling, skin irritation, and corneal irritation, while severe allergic reactions or anaphylactic shock may rarely occur. This drug can cause irritation if it comes into contact with the eyes, therefore it should not be used near the eyes or ears; if contact occurs, it should be washed immediately with clean water. Overdosage may lead to severe central nervous system and cardiovascular disturbances, so if symptoms arise, immediate medical treatment should be sought. The effects on the fetus during pregnancy have not been reported, but this drug should only be used when the benefits outweigh the risks, under a doctor's judgment. Nursing mothers should also be cautious as this drug may be excreted in breast milk. It should only be used sparingly in children, especially infants under 3 months, and should not be applied to the genital mucosa. The risk of methemoglobinemia may increase when used in conjunction with other medications, so if other medications are taken, it is essential to consult with a doctor or pharmacist. There have been reports of carcinogenic potential with high doses or long-term use of this drug, so it is important to adhere to the recommended dosage and duration of use.

Serious side effects

• Methemoglobinemia
• anaphylactic shock
• seizures
• coma
• arrhythmias
• death
• corneal irritation
• severe allergic reactions

Mild side effects

• Temporary local reactions such as pallor
• redness
• swelling
• mild initial burning sensation
• itching
• tingling
• skin irritation
• corneal irritation

This medicine may be sensitive to air or moisture, so it should be stored in a tightly sealed container. It is important to maintain a storage temperature between 1 to 30 degrees Celsius. This will help maintain the drug's effectiveness over time.

Appearance

White cream

Package unit

For domestic use - 10 grams/tube, For domestic use - 100 grams/tube, For domestic use - 500 grams/bottle, For export - 10 grams/tube, For export - 100 grams/tube, For export - 500 grams/bottle, For export - 30 grams/tube