Lercanidipine Tablets (Lercanidipine Hydrochloride)

Adult dose

As Lercanidipine Hydrochloride, take 5 to 10 mg once daily orally at least 15 minutes before a meal. The dose may be increased to 20 mg according to the patient's symptoms. Dose adjustment takes up to 2 weeks to observe the maximum antihypertensive effect, thus it should be made gradually.

This drug should not be administered to certain patients. For example, those who are allergic to this drug or similar drugs, women who are pregnant or may become pregnant, and individuals who are breastfeeding should not take this drug. Additionally, patients with heart problems, very poor liver or kidney function, those who have recently suffered a myocardial infarction, patients undergoing dialysis, and children or adolescents under 18 years of age are also not recommended to use this drug. This drug contains lactose, so those with lactose intolerance or related genetic disorders should not take it. Caution is required for specific patient groups when using this drug. For example, individuals with problems with cardiac pacemakers or weak heart function, those with mild to moderate liver or kidney disorders, or those with a history of angina should use this drug cautiously. Also, alcohol consumption may enhance the blood pressure-lowering effect of this drug, so care is needed, and special caution is required for the elderly. While taking this drug, symptoms may occur such as flushing, swelling of hands and feet, and rapid heart rate, and rarely, low blood pressure or chest pain may occur. Symptoms such as headache, dizziness, fatigue, indigestion, nausea, abdominal pain, and diarrhea may also be experienced. It is important to have regular liver function tests as liver function abnormalities may occur, and if abnormalities are found, the medication should be stopped immediately. This drug may cause drowsiness or lethargy, so caution is required when driving or operating machinery. This drug is metabolized in the liver, and interactions may occur when taken with specific drugs. Particularly, medicines that inhibit or activate enzymes involved in liver metabolism should be discussed with a doctor or pharmacist before concurrent use. It is advisable to avoid taking this drug with grapefruit juice as it may increase drug concentrations. Women who are pregnant or breastfeeding should not take this drug, and those planning for pregnancy should consult with healthcare professionals. The safety and efficacy of this drug have not been established in children or adolescents, therefore, it should not be used in these populations. In case of overdose, severe hypotension or heart problems may occur, so if any abnormal symptoms arise, medical attention should be sought immediately. Finally, this drug should be kept out of reach of children, and it is safe not to transfer it to other containers.

Serious side effects

• Hypotension
• chest pain
• angina
• cold sweat
• shortness of breath
• liver dysfunction
• severe allergic reactions
• severe neurological symptoms
• severe edema or urinary disturbances

Mild side effects

• Flushing (including facial flushing)
• peripheral edema
• palpitations
• tachycardia
• headache
• dizziness
• lethargy
• fatigue
• drowsiness
• neurosis

This drug should be stored in a tightly closed container to avoid exposure to air or moisture. It is advisable to maintain a storage temperature between 1 degree and 30 degrees Celsius. This helps to maintain the effectiveness and safety of the medication over a long period.

Appearance

Yellow round film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle